Results 51 to 60 of about 8,234,457 (404)

Monitoring of veterinary drug residues in livestock products with antimicrobial resistance

Applied Biological Chemistry
Antimicrobial resistance (AMR) in animal-derived products remains a global concern, while reports on veterinary drug (VD) residues in such products are relatively rare.
Dahae Park, Yu Ra Kim, Ji Young Kim, Jang-Duck Choi, Guiim Moon, Dong Woo Shin   +5 more
doaj   +1 more source

Papyrus: a large-scale curated dataset aimed at bioactivity predictions

Journal of Cheminformatics, 2023
With the ongoing rapid growth of publicly available ligand–protein bioactivity data, there is a trove of valuable data that can be used to train a plethora of machine-learning algorithms.
O. J. M. Béquignon, B. J. Bongers, W. Jespers, A. P. IJzerman, B. van der Water, G. J. P. van Westen   +5 more
doaj   +1 more source

Artificial Intelligence and the Future of the Drug Safety Professional

Drug Safety, 2018
The healthcare industry, and specifically the pharmacovigilance industry, recognizes the need to support the increasing amount of data received from individual case safety reports (ICSRs).
Karolina Danysz, Salvatore Cicirello, Edward Mingle, Bruno Assuncao, Niki Tetarenko, Ruta Mockute, Danielle Abatemarco, Mark Widdowson, Sameen Desai   +8 more
semanticscholar   +1 more source

Risk Perception and Drug Safety Evaluation [PDF]

, 1991
The authors present a Risk communication framework based on a survey of empirical research concerning public Risk perceptions.
Vertinsky, Ilan B., Wehrung, Donald A.
core   +1 more source

Pazopanib Combined With Vincristine and Irinotecan in Relapsed Wilms Tumor: Encouraging Outcomes in a Heavily Pretreated Pediatric Cohort

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background While Wilms tumor (WT) typically has a favorable prognosis, relapsed cases—especially those with high‐risk histology—remain therapeutically challenging after intensive frontline therapy. The combination of vincristine and irinotecan has demonstrated activity in pediatric solid tumors, and pazopanib, a multi‐targeted tyrosine kinase ...
Maria Debora De Pasquale, Alessandro Crocoli, Giuseppe Maria Milano, Pierluigi Di Paolo, Francesca Diomedi Camassei, Ida Russo, Annalisa Serra   +6 more
wiley   +1 more source

Enhancing pharmacogenomic data accessibility and drug safety with large language models: a case study with Llama3.1. [PDF]

Exp Biol Med (Maywood)
Li D, Wu L, Lin YC, Huang HY, Cotton E, Liu Q, Chen R, Huang R, Zhang Y, Xu J.   +9 more
europepmc   +3 more sources

Today's Challenges to De-Risk and Predict Drug Safety in Human "Mind-the-Gap".

Toxicological Sciences, 2018
Current gaps in drug safety sciences can result from the inability (1) to identify hazard across multiple target organs, (2) to predict and risk assess with certainty against drug safety liabilities for the major target organs, (3) to optimally manage ...
R. Weaver, J. Valentin
semanticscholar   +1 more source

Stereotactic Body Radiation Therapy for Pediatric, Adolescent, and Young Adult Patients With Osteosarcoma: Local Control Outcomes With Dosimetric Analysis

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background/Objectives Osteosarcoma is a radioresistant tumor that may benefit from stereotactic body radiation therapy (SBRT) for locoregional control in metastatic/recurrent disease. We report institutional practice patterns, outcomes, toxicity, and failures in osteosarcoma patients treated with SBRT.
Jenna Kocsis, Shauna R. Campbell, Jonathan Jang, Eashwar Somasundaram, Chandana A. Reddy, Jacob G. Scott, Lilyana Angelov, Peter M. Anderson, Matteo Trucco, Zachary Burke, Lukas Nystrom, Nathan Mesko, Anthony Magnelli, Erin S. Murphy   +13 more
wiley   +1 more source

Simultaneous determination of 31 Sulfonamide residues in various livestock matrices using liquid chromatography-tandem mass spectrometry

Applied Biological Chemistry
The widespread use of sulfonamides can result in the residue of sulfonamides in the foods of animal origin that are the major concerns of consumers and regulatory bodies due to their adverse reaction such as the development of antibiotic resistance.
Yu Ra Kim, Sunyoung Park, Ji Young Kim, Jang-Duck Choi, Gui-Im Moon   +4 more
doaj   +1 more source

Arrests for Drug Offenses in Alaska: 2000-2011 [PDF]

, 2013
This fact sheet presents data on arrests for drug offenses made by Alaska police agencies for the period 2000 through 2011. The report presents drug offense arrest information for both adults and juveniles for the 12-year period, including number of drug
Myrstol, Brad A.
core