Results 71 to 80 of about 8,234,457 (404)
Evidence and Extrapolation: Mechanisms for Regulating Off-Label Uses of Drugs and Devices [PDF]
, 2014 A recurring, foundational issue for evidence-based regulation is deciding whether to extend governmental approval from an existing use with sufficient current evidence of safety and efficacy to a novel use for which such evidence is currently lacking ...
Abbott, Ryan, Ayres, Ian
core +3 more sources
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Background The delipid extracorporeal lipoprotein filter from plasma (DELP) treatment can effectively reduce blood lipid, increase blood flow, and improve neurological deficits in patients with acute ischemic stroke (AIS). However, its effect on vision and retinal microcirculation in stroke patients has never been reported.
Ning Li +9 more
wiley +1 more source
Investigation of safety and efficacy of febantel and fenbendazole in fish and exposure assessment
Applied Biological ChemistryFish are susceptible to blood-sucking parasite infections, which cause severe anemia, dyspnea, and ultimately death. However, veterinary drugs available for fish to treat such infectious diseases are lacking; thus, livestock drugs have been repurposed as
Min Ji Kim +3 more
doaj +1 more source
Scientific Reports, 2022 Salmonella infections represent an important public health problem. In 2018, a multistate outbreak of S. enterica subsp. enterica serovar Thompson infection associated with contaminated chocolate cakes in schools was reported in South Korea.
Woojung Lee +9 more
doaj +1 more source
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
A rat model of Immunologic and hypertensive kidney injury
Scientific ReportsNon-surgical rodent chronic kidney disease (CKD) models for both glomerular and tubular injuries are currently limited. The current study aimed to develop a rat model of CKD by combining anti-Fx1A with N(ω)-Nitro-L-Arginine Methyl Ester (L-NAME ...
Seo-Kyoung Hwang +10 more
doaj +1 more source
Molecules, 2020 In this work, liquid chromatography–tandem mass spectrometry (LC-MS/MS) method was developed and validated for screening and confirmation of 64 illicit compounds in dietary supplements.
Dasom Shin +3 more
doaj +1 more source
Assessing Drug Safety in Children - The Role of Real-World Data.
New England Journal of Medicine, 2018 Assessing Drug Safety in Children There are substantial gaps in evidence regarding the safety of many drugs in children.
A. McMahon, G. D. Dal Pan
semanticscholar +1 more source
Improving Drug Safety: The Importance of Postmarking Drug Surveillance [PDF]
, 2004 Improved postmarketing surveillance system may reduce the number of adverse reactions to prescription drugs that under the current system continue to rise as the number of prescriptions written in the U.S ...
James Nyberg, Robert N. Butler
core
Trends and correlates of substance use disorders among probationers and parolees in the United States 2002–2014 [PDF]
, 2016 BACKGROUND: Substance use and crime/recidivism are irrevocably linked. We explore the nuances of this association by highlighting the prevalence, trends, and correlates of substance use dsorders in a large group of probationers/parolees.
DeLisi, Matt +5 more
core +1 more source