Results 121 to 130 of about 4,907,325 (259)

Methadone use 'brings stability', study finds.

open access: yes, 2018
The first-ever study in Ireland on long-term participants in methadone maintenance treatment has found that while it can bring some stability to users, more supports are needed to allow for social reintegration.
Baker, Noel
core  

THE IMPORTANCE OF CHROMATOGRAPHICALLY PURIFIED EXCIPIENTS

open access: yesРазработка и регистрация лекарственных средств, 2019
In the present work critical importance and benefits of Super Refined excipients for drug stability, integrity and safety are described. It was shown, that impurities can disrupt API and cause cell irritation.
G. J. Rizzo, K. H. Chen
doaj  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Batch analysis and stability data for PfAMA1-DiCo Drug Product.

open access: yes, 2016
Batch analysis and stability data for PfAMA1-DiCo Drug Product.
Hubert Mertens (3190524)   +13 more
core   +1 more source

Stability of drug additives to peritoneal dialysate.

open access: yes, 1995
Click on the Resource Link to access the article (may not be free).OBJECTIVE: The primary literature was reviewed to determine the stability of drug additives in peritoneal dialysis solutions.DATA SOURCES: A MEDLINE search and retrieval, covering the ...
Bailie, G R, Kane, Michael P
core   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

EFFECTS OF DOMESTIC STORAGE CONDITIONS ON THE PHYSICAL INTEGRITY AND ASSAY OF IBUPROFEN TABLETS

open access: yesInfarma: Pharmaceutical Sciences
Improper domestic storage of medicines may compromise product quality and patient safety, particularly for over-the-counter drugs. This study evaluated the effects of different household storage conditions on the physical integrity and assay of ibuprofen
Adriana Gonçalves Ferreira Deo   +1 more
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Victorian Drug Household Survey, 1993

open access: yes, 2019
The Victorian Drug Household Survey (VDHS) was conducted as an extension to the fourth National Campaign Against Drugs and Alcohol (NCADA) National Drug Household Survey (NDHS).
Harrison, Stanford
core   +1 more source

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