Formation, drug-release kinetics and solution-stability of N-acetyl-N-carboxymethyl chitosan nanoparticles as potential drug carriers [PDF]
, 2013 Nano-aggregates of N-acetyl-N-carboxymethyl chitosan (NCac) were studied at 0.5 mg.mL-1 using pyrene fluorimetry analysis in 0.1 mol.L-1 phosphate buffer (pH 7.4).
Sierakowski, Maria Rita; BioPol , Chemistry Department, Federal University of Paraná – UFPR, P.O. 19081, Curitiba (PR), 81531-980, Brazil. +3 more
core
Stability Indicating HPLC Method Development: A Review
, 2019 High performance liquid chromatography is one of the most accurate method widely used for quantitative as well as qualitative analysis of drug product and it is used for determining drug product stability.
Saudagar, R B, Mahale, Manisha M
core +1 more source
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Revista de Saúde Pública, 2013 Com base em análise documental, foram discutidas e problematizadas as limitações associadas à utilização de organizadores e cortadores de comprimidos, como questão de saúde pública. Os organizadores destinados ao armazenamento e transporte de comprimidos
Caroline Ribeiro de Borja-Oliveira
doaj
Long-term stability of liposomal mycobacteriophage D29: A comprehensive in vitro assessment
Биопрепараты: Профилактика, диагностика, лечениеINTRODUCTION. The spread of antibiotic-resistant mycobacteria necessitates new therapeutic approaches for tuberculosis, phage therapy being one of them.
V. V. Avdeev +2 more
doaj +1 more source
Drug Stability: ICH versus Accelerated Predictive Stability Studies. [PDF]
Pharmaceutics, 2022 González-González O +6 more
europepmc +1 more source
Drug addicts need more than simply harm reduction.
, 2019 Dún Laoghaire-Rathdown Drug and Alcohol Taskforce recently published a report detailing the experiences of long-term methadone users. Some participants described how the stability of methadone had saved their life, but they were still imprisoned by a ...
Costello, Patrick
core
Chitosan based hydrogels for transmucosal drug delivery
, 2013 The aim of this thesis was the formulation of new chitosan based delivery systems for transmucosal drug administration. Transmucosal routes, such as buccal, vaginal and nasal routes, allow the circumvention of the hepatic first pass metabolism and avoid ...
Abruzzo, Angela <1984>
core +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Mechanochemical Oxidative Degradation of Thienopyridine Containing Drugs: Toward a Simple Tool for the Prediction of Drug Stability. [PDF]
ACS Cent Sci, 2023 Krake EF +8 more
europepmc +1 more source