Results 141 to 150 of about 8,056,631 (393)

Mechanochemical Oxidative Degradation of Thienopyridine Containing Drugs: Toward a Simple Tool for the Prediction of Drug Stability. [PDF]

ACS Cent Sci, 2023
Krake EF, Backer L, Andres B, Baumann W, Handler N, Buschmann H, Holzgrabe U, Bolm C, Beweries T.   +8 more
europepmc   +1 more source

Characterization of an effective drug carrier system for improved oxidative and thermal stability of essential fatty acids: a review [PDF]

, 2022
M. Jude Jenita, Udayasoorian Lalithapriya, Renuka Venkatachalapathy, M. Sukumar   +3 more
openalex   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Stability and Compatibility of Ramosetron with Midazolam in 0.9% Sodium Chloride Injection for Postoperative Nausea and Vomiting Administration

Drug Design, Development and Therapy, 2020
Jingsheng Xia,1 Peng Chen2 1Department of Pharmacy, Wuhan Third Hospital, Tongren Hospital of Wuhan University, Wuhan, Hubei 430060, People’s Republic of China; 2Department of Pharmacy, Renmin Hospital of Wuhan University, Wuhan, Hubei 430060 ...
Xia J, Chen P
doaj  

Replicates Number for Drug Stability Testing during Bioanalytical Method Validation-An Experimental and Retrospective Approach. [PDF]

Molecules, 2022
Gniazdowska E, Goch W, Giebułtowicz J, Rudzki PJ.   +3 more
europepmc   +1 more source

The study on the stability of a drug. Can a product have life? [PDF]

, 2005
Xavier Soláns
openalex   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

Molecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard, Sarmad Mehmood, Eva Boysen Fynboe Ebert, Peter Meldgaard, Anindya Dutta, Boe S. Sorensen   +5 more
wiley   +1 more source

Drugs, Crime, Space, and Time: A Spatiotemporal Examination of Drug Activity and Crime Rates [PDF]

, 2020
To take stock of the “neighborhood effects” of drug activity, we combined theoretical insights from the drugs and crime and communities and place literatures in examining the longitudinal relationship between drug activity and crime rates at more ...
Contreras, C, Hipp, JR
core  

Impact of Quantisal^® Oral Fluid Collection Device on Drug Stability. [PDF]

Front Toxicol, 2021
Riggio M, Dave KA, Koscak B, Blakey M, Appleton C.   +4 more
europepmc   +1 more source