Results 181 to 190 of about 8,056,631 (393)

The effects of tropical climate on the stability of emergency drugs used in ambulances under real EMS situations

open access: hybrid
Sittichok Leela-Amornsin   +5 more
openalex   +2 more sources

Novel imidazotetrazine derivatives overcome temozolomide resistance in glioblastoma by inducing ferroptosis and apoptosis

open access: yesCell Death Discovery
Glioblastomas (GBM) is a highly malignant primary brain tumor with poor prognosis despite standard treatments of surgery, radiotherapy, and chemotherapy.
Heng Yang   +8 more
doaj   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

Understanding Molecular Mechanism of Biologics Drug Delivery and Stability from NMR Spectroscopy.

open access: yesAdvanced Drug Delivery Reviews, 2021
Pyae Phyo   +5 more
semanticscholar   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

open access: yesMolecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li   +10 more
wiley   +1 more source

Ultrasonic-Assisted Degradation of Metformin from Pharmaceutical Effluent: Process Optimization via Response Surface Methodology [PDF]

open access: yesJournal of Environmental Health and Sustainable Development
Introduction: Metformin, an extremely prescribed antidiabetic medication, is discharged with minimal or no processing and remains during the usual wastewater treatment procedures.
Shital P. Dehankar, Ratnadip R. Joshi
doaj  

Drug stability [PDF]

open access: yesEuropean Journal of Hospital Pharmacy, 2012
openaire   +2 more sources

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