Results 261 to 270 of about 1,261,260 (337)

Calcium alginate medicated dressing for enhanced absorption in diabetic foot ulcer management. [PDF]

Sci Rep
Puri GK, Jania RK, Upadhye V, Sharma MC, Hassan SMS, Alsaidan OA, Hajare ST.   +6 more
europepmc   +1 more source

Drug Facilitated Sexual Assault: Detection and Stability of Benzodiazepines in Spiked Drinks Using Gas Chromatography-Mass Spectrometry

, 2014
Lata Gautam, Sarah D. Sharratt, Michael Cole   +2 more
openalex   +2 more sources

Modelling Atherosclerotic Plaque Cap Mechanics: Microcalcifications Reduce Mechanical Properties in Mesenchymal Stromal Cell‐Based Model

Advanced Biology, EarlyView.
This study develops a tissue‐engineered model of the atherosclerotic cap using human mesenchymal stromal cells (MSCs). After 2 weeks of culture to produce a collagenous matrix, a mineralizing medium induces microcalcifications over 4 weeks. These constructs, imaged with second harmonic generation microscopy, lead to reduced ultimate stress at rupture ...
Imke L. Jansen, Deniz Şahin, Frank J.H. Gijsen, Eric Farrell, Kim van der Heiden   +4 more
wiley   +1 more source

Nanoparticle tools for maximizing oral drug delivery. [PDF]

Braz J Med Biol Res
Cahyani DM, Mubarok AS, Hariawan BS, Amalina I, Drake P, Parumasivam T, Sahu RK, Rijal MAS, Sari R, Miatmoko A.   +9 more
europepmc   +1 more source

Microphysiological Glomerular Filtration Barriers: Current Insights, Innovations, and Future Applications

Advanced Biology, EarlyView.
The glomerular filtration barrier (GFB) is the first step of blood filtration by the kidneys. The concerning increase of kidney diseases makes the development of new models essential. In this context, microphysiological glomerular filtration barriers focus on closely reproducing the physiological architecture of the in vivo GFB: podocytes, glomerular ...
Manon Miran, Kieu Ngo, David Buob, Hanna Debiec, Pierre Ronco, Guillaume Perry   +5 more
wiley   +1 more source

Structure-based molecular screening and dynamic simulation of phytocompounds targeting VEGFR-2: a novel therapeutic approach for papillary thyroid carcinoma. [PDF]

Front Pharmacol
Wang S, Zhang L, Zhang W, Zeng X, Mei J, Xiao W, Yang L.   +6 more
europepmc   +1 more source

Targeting Oncoprotein Stability Overcomes Drug Resistance Caused by FLT3 Kinase Domain Mutations

, 2014
Chuanjiang Yu, Rama Krishna Kancha, Justus Duyster   +2 more
openalex   +2 more sources

Investigating the Cellular Effects of GALC Dosing in Enzyme Replacement Therapy for Krabbe Disease Supports the Role of Nanomedicine

Advanced Biology, EarlyView.
A detailed workflow for recombinant GALC production and characterization is presented to support enzyme replacement therapy for Krabbe disease. In vitro assays demonstrate that physiological GALC doses restore enzymatic activity and autophagic flux without affecting cell viability, whereas higher doses impair autophagy and reduce viability.
Ambra Del Grosso, Sara Carpi, Laura Colagiorgio, Miriam De Sarlo, Mariacristina Gagliardi, Marco Cecchini   +5 more
wiley   +1 more source

Comment on Hermeling et al. Nano-Dry-Melting: A Novel Technology for Manufacturing of Pharmaceutical Amorphous Solid Dispersions. <i>Pharmaceutics</i> 2022, <i>14</i>, 2145. [PDF]

Pharmaceutics
Miller DA, Kucera SU, Ellenberger D, Davis D, Williams RO.   +4 more
europepmc   +1 more source

Stability of HIV-1 Nucleic Acids in Dried Blood Spot Samples for HIV-1 Drug Resistance Genotyping

, 2015
Susan C. Aitken, Carole L. Wallis, Wendy Stevens, Tobias Rinke de Wit, Rob Schuurman   +4 more
openalex   +2 more sources