Results 261 to 270 of about 8,084,609 (393)

Influence of molecular weight of carriers and processing parameters on the extrudability, drug release, and stability of fenofibrate formulations processed by hot-melt extrusion

, 2015
Bader B. Alsulays, Jun-Bom Park, Sultan Alshehri, Joseph T. Morott, Saad M. Alshahrani, Roshan V. Tiwari, Abdullah Alshetaili, Soumyajit Majumdar, Nigel Langley, Karl Kolter, Andreas Gryczke, Michael A. Repka   +11 more
openalex   +1 more source

The Aging Blood: Cellular Origins, Circulating Drivers, and Therapeutic Potential

Aging and Cancer, EarlyView.
As a conduit linking all organs, the blood system both reflects and actively drives systemic aging. This review highlights how circulating pro‐aging and antiaging factors and age‐associated hematopoietic stem cell dysfunction contribute to immunosenescence and multi‐organ decline, positioning the hematopoietic system as a target for aging intervention.
Hanqing He, Jianwei Wang
wiley   +1 more source

Self-assembling nanocomposites for smart drug delivery: towards personalized and stimuli-responsive therapeutics. [PDF]

RSC Adv
Emadi R, Amiri Z, Mortazavi Moghadam F, Raoufi S, Zargar Moradi M, Asadi S, C Cho W, Park JH, Voosough A, Ramezani Farani M, Hwang SK, Huh YS.   +11 more
europepmc   +1 more source

B-303 Stability of Antipsychotic Drugs in Patient Serum and Plasma Clinical Samples [PDF]

M S Konrath, Adrienne Drisgill, Daniel Kozo, Michelle L. Hilaire, S. J. Salamone   +4 more
openalex   +1 more source

Tracking Motor Progression and Device‐Aided Therapy Eligibility in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterise the progression of motor symptoms and identify eligibility for device‐aided therapies in Parkinson's disease, using both the 5‐2‐1 criteria and a refined clinical definition, while examining differences across genetic subgroups.
David Ledingham, Sahana Sathyanarayana, Charlotte B. Stewart, Robyn Iredale, Victoria Foster, Debra Galley, Mark Baker, Nicola Pavese   +7 more
wiley   +1 more source

Integrating In Vitro Analytics for Improved Antibody-Drug Conjugate Candidate Selection. [PDF]

Cancers (Basel)
Del Solar V, Saleh A, Di Tacchio A, Becciolini LS, Kang GD, Jackowska B, Hu Y, Gong C, Zhang A, Hostetler L, Lee M, Khan AH, Mitra A, Ahmed M, Tickle D, Vijayakrishnan B.   +15 more
europepmc   +1 more source

Accelerated Predictive Stability Testing: Accelerating Registration Phase and Application of Reduced Designs for Shelf-Life Determination of Parenteral Drug Product [PDF]

Lara Pavčnik, Mateja Prunk, Tina Trdan Lušin, Robert Roškar   +3 more
openalex   +1 more source

Physico-Chemical Strategies to Enhance Stability and Drug Retention of Polymeric Micelles for Tumor-Targeted Drug Delivery.

Macromolecular Bioscience, 2017
Yang Shi, T. Lammers, G. Storm, W. Hennink   +3 more
semanticscholar   +1 more source

Systemic T Cell Receptor Profiling Reveals Adaptive Immune Activation and Potential Immune Signatures of Diagnosis and Brain Atrophy in Epilepsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Epilepsy is increasingly associated with immune dysregulation and inflammation. The T cell receptor (TCR), a key mediator of adaptive immunity, shows repertoire alterations in various immune‐mediated diseases. The unique TCR sequence serves as a molecular barcode for T cells, and clonal expansion accompanied by reduced overall TCR ...
Yong‐Won Shin, Sang Bin Hong, Yong Woo Shin, Inpyeong Hwang, Jaeseong Oh, Jihyeon Choi, Narae Kim, Jangsup Moon, Keun‐Hwa Jung, Kyung‐Il Park, Ki‐Young Jung, Kon Chu, Sang Kun Lee   +12 more
wiley   +1 more source

Metabolic Stability of Fluorinated Small Molecules: A Physical Organic Chemistry Perspective. [PDF]

J Med Chem
Bhattarai P, Trombley TA, Altman RA.
europepmc   +1 more source