Results 301 to 310 of about 8,056,631 (393)

Effectiveness and Safety of Nusinersen and Risdiplam in Spinal Muscular Atrophy: A Systematic Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Spinal Muscular Atrophy (SMA) is a rare genetic disorder marked by progressive muscle weakness and mobility loss. It has a profound physical, emotional and social impact on patients and caregivers, requiring comprehensive medical and supportive care.
Amin Mehrabian, Peter Auguste, Amy Grove, Anna Brown, Janette Parr, Mubarak Patel, Furqan Butt, Jeremiah Donoghue, Mehdi Yousefi, Jo Parsons   +9 more
wiley   +1 more source

The future of vesicular drug delivery: transferosomes in therapeutic advancement-applications, innovations and challenges. [PDF]

Biomed Eng Online
Medhi J, Thalluri C, Vasam M, Bukke SPN.
europepmc   +1 more source

Evaluation of the Efficacy and Safety of Satralizumab in a Pregnant NMOSD Patient With AQP4/MOG‐IgG Dual Seropositive: A Case Report

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Neuromyelitis Optica Spectrum Disorder (NMOSD) is a chronic autoimmune neuroinflammatory disease, typically characterized by antibodies against aquaporin 4 (AQP4‐IgG) or myelin oligodendrocyte glycoprotein (MOG‐IgG). Simultaneous seropositivity for both antibodies in a single patient is exceedingly rare.
Yeting Luo, Shuhua Xie, Xianghong Liu
wiley   +1 more source

Curcumin-Loaded Nanoscale Metal-Organic Frameworks for Therapeutic Applications in Cancer. [PDF]

Nanomaterials (Basel)
Tutunchi H, Nabipour H, Rohani S.
europepmc   +1 more source

Lessons Learned From a Delayed‐Start Trial of Modafinil for Freezing of Gait in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Freezing of gait (FOG) in people with Parkinson's disease (PwPD) is debilitating and has limited treatments. Modafinil modulates beta/gamma band activity in the pedunculopontine nucleus (PPN), like PPN deep brain stimulation. We therefore tested the hypothesis that Modafinil would improve FOG in PwPD.
Tuhin Virmani, Lakshmi Pillai, Reid D. Landes, Aliyah Glover, Shannon Doerhoff, Jennifer Kleiner, Mitesh Lotia, Rohit Dhall, Edgar Garcia‐Rill   +8 more
wiley   +1 more source

Selection of Solubility Enhancement Technologies for S-892216, a Novel COVID-19 Drug Candidate. [PDF]

Pharmaceutics
Ohashi R, Otake S, Murata T, Watari R, Yoshida S, Kitade M, Kondo D, Kimura G.   +7 more
europepmc   +1 more source

Predicting Epileptogenic Tubers in Patients With Tuberous Sclerosis Complex Using a Fusion Model Integrating Lesion Network Mapping and Machine Learning

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Accurate localization of epileptogenic tubers (ETs) in patients with tuberous sclerosis complex (TSC) is essential but challenging, as these tubers lack distinct pathological or genetic markers to differentiate them from other cortical tubers.
Tinghong Liu, Qi Wang, Suhui Kuang, Dezhi Cao, Ping Ding, Shaohui Zhang, Haihua Wei, Zhirong Wei, Jinshan Xu, Xinyu Huang, Bing Liu, Shuli Liang   +11 more
wiley   +1 more source

NSUNs-driven dysregulation: the next frontier in targeted cancer therapy? [PDF]

Cell Death Dis
Zhao Y, Zhang Y, Zhou H, Zhang L, Guo J, Tan Y, Wu T, Peng Y, Che Y, Pei Z, Li J, Fu B, Wei M, Wu G, Hu X, Wu H.   +15 more
europepmc   +1 more source

Silymarin and Silybin: Rejuvenating Traditional Remedies with Modern Delivery Strategies. [PDF]

Pharmaceutics
Li X, Zhu H, Wang Y, Zhang X, Yang Z, Yan X, Yu Q.   +6 more
europepmc   +1 more source

PLGA-Based Co-Delivery Nanoformulations: Overview, Strategies, and Recent Advances. [PDF]

Pharmaceutics
Stevanović MM, Qian K, Huang L, Vukomanović M.   +3 more
europepmc   +1 more source