Novel Findings about Double-Loaded Curcumin-in-HPβcyclodextrin-in Liposomes: Effects on the Lipid Bilayer and Drug Release [PDF]
In this study, the encapsulation of curcumin (Cur) in “drug-in-cyclodextrin-in-liposomes (DCL)” by following the double-loading technique (DL) was proposed, giving rise to DCL–DL.
Fernández Romero, Ana María+4 more
core +2 more sources
Stability investigation of total parenteral nutrition admixture prepared in a hospital pharmacy [PDF]
Background/Aim. In the cases when nutrition of patients can not be orally nor enterally performed, parenteral nutrition is a method of the therapy that provides more successful and rapid recovery. In that way, hospitalization can be significantly shorter,
Mirković Dušica+3 more
doaj +1 more source
Depth of anesthesia control using internal model control techniques [PDF]
The major difficulty in the design of closed-loop control during anaesthesia is the inherent patient variability due to differences in demographic and drug tolerance.
Anna, Shahab, Wen, Peng
core +2 more sources
Janus kinase (JAK) inhibitors, such as tofacitinib (Xeljanz) and filgotinib (Jyseleca), have been approved for treatment of ulcerative colitis with several other JAK inhibitors in late-stage clinical trials for inflammatory bowel disease (IBD).
Vipul Yadav+16 more
doaj +1 more source
Formulation and evaluation of floating mucoadhesive alginate beads for targetingHelicobacter pylori [PDF]
Objectives: There are various obstacles in the eradication of Helicobacter.pylori (H. pylori) infections, including low antibiotic levels and poor accessibility of the drug at the site of the infection.
Adebisi+59 more
core +1 more source
This study investigates the complexation of mefloquine hydrochloride by cyclodextrins to improve its solubility in order to design an oral solution.
Amaury Durand+4 more
doaj +1 more source
A systematic approach to the formulation of anti-onychomycotic nail patches [PDF]
Nail patches have a potential role as drug carriers for the topical treatment of nail diseases such as onychomycosis, a common condition. O ur aim was therefore to develop a systematic and novel appr oach to the formulat ion of a simple drug -in-adhesive
Charalambides, MN+5 more
core +1 more source
Challenges of Colistin Use in ICU and Therapeutic Drug Monitoring: A Literature Review
The emerging resistance of Gram-negative bacteria is a growing problem worldwide. Together with the financial cost, limited efficacy, and local unavailability of newer antibiotics or their combinations, it has led to the reintroduction of colistin as a ...
Jitka Rychlíčková+3 more
doaj +1 more source
Development of a predictive model for the long term stability assessment of drug-in-adhesive transdermal films using polar pressure sensitive adhesives as carrier/matrix. [PDF]
Drug crystallization in transdermal drug delivery systems is a critical quality defect. The impact of drug load and hydration on the physical stability of polar (acrylic) drug-in-adhesive (DIA) films was investigated with the objective to identify ...
Ashton, Mark+4 more
core +1 more source
The following review focuses on the manufacturing and parameterizing of ocular drug delivery systems (DDS) using polymeric materials to create soft contact lenses.
Iwona Rykowska+3 more
doaj +1 more source