Results 161 to 170 of about 3,800,890 (227)

Toxic Reactions Due to Drug Synergism and Antagonism

open access: bronzeAnesthesia & Analgesia, 1968
Grosshandler Sl, Kampine Jp, Hanschel Eo
openaire   +4 more sources
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Computational studies of drug repurposing and synergism of lopinavir, oseltamivir and ritonavir binding with SARS-CoV-2 protease against COVID-19

Journal of Biomolecular Structure and Dynamics, 2020
A novel coronavirus (SARS-CoV-2) has caused a major outbreak in humans all over the world, and it is the latest pandemic in the series of other infectious diseases.
Nisha Muralidharan   +3 more
semanticscholar   +1 more source

Communicating Synergism in Drug Combination Studies

Arzneimittelforschung, 2011
Isobolograms are used to identify synergistic effects of drugs given in combination. However, the traditional isobologram provides only a qualitative determination of synergism. The present report describes two procedures for quantifying the synergistic actions of drugs based on isobolographic plots.
Harlan E. Shannon, Jesse Brodkin
openaire   +3 more sources

A Fatality Due to Drug Synergism

Medicine, Science and the Law, 1982
Thioridazine is a phenothiazine tranquillizer with specificity for psychotherapeutic action. It is well tolerated but will induce changes in myocardial repolarization which are further aggravated in the presence of low blood potassium levels. Fatalities due to overdosage of thioridazine are rare and those associated with therapeutic dosage and cross ...
openaire   +3 more sources

Synergism in Drug Treatment of Familial Hypercholesterolemia [PDF]

open access: possible, 1980
The monogenic disorder familial hypercholesterolemia (FH) is associated with a high risk of premature coronary arteriosclerosis, largely attributable to a 2-3 fold increase in levels of low density lipoproteins (LDL) in serum. Heretofore, no regimen of drug therapy or surgical intervention has been reported which is capable of lowering levels of low ...
M. J. Malloy   +3 more
openaire   +1 more source

Synergism between Histamine, Antihistamines, and Hypnotic Drugs†

Journal of the American Pharmaceutical Association (Scientific ed.), 1952
The synergism between antihistamines and the barbiturate Evipal was studied in mice. Similar synergism was found between histamine and barbiturates and between antihistamines and ether. The possible clinical usefulness of these findings is discussed. Thephorin, in mice, shows a synergistic effect with barbiturates or ether similar to that of Benadryl ...
Clara M. Ambrus   +4 more
openaire   +3 more sources

The effect of crocin on the proliferation, inflammation, drug synergism, and angiogenesis in breast cancer

PHYTONutrients
Radiation, chemotherapy, and surgery are common treatments for breast cancer. These approaches, however, could only improve the odds of surviving. Using herbal medicines like crocin is now necessary to improve cancer treatment, particularly for breast ...
Seyed Hossein   +2 more
semanticscholar   +1 more source

A Test for Synergism Between Two Drugs

Applied Statistics, 1976
A likelihood ratio test is devised to detect the presence of synergism between two drugs which have similar actions. An example is given.
S. C. Darby, M. J. Ellis
openaire   +2 more sources

Co-delivery of Docetaxel and Disulfonate Tetraphenyl Chlorin in One Nanoparticle Produces Strong Synergism between Chemo- and Photodynamic Therapy in Drug-Sensitive and -Resistant Cancer Cells.

Molecular Pharmaceutics, 2018
Cancer therapies based on the combinations of different drugs and/or treatment modalities are emerging as important strategies for increasing efficacy and cure, decreasing unwanted toxicity, and overcoming drug resistance, provided that optimized drug ...
Elisa Gaio   +6 more
semanticscholar   +1 more source

Synergism of Three Antimicrobial Drugs

Nature, 1966
COMBINED therapy with two or more antibacterial drugs may be useful in the treatment of an individual case, and in discouraging the development of resistance1. A formula was previously presented which could be used in evaluating the combined effect of two drugs2.
Deborah Kaplan, Walter Koch
openaire   +3 more sources

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