Results 261 to 270 of about 43,453 (280)

Synergism between staurosporine and drugs inducing endoplasmic reticulum stress

Biochemical Pharmacology, 2006
Drugs causing endoplasmic reticulum or mitochondrial dysfunction may trigger apoptosis in eukaryotic cells. The thiol reagent dithiothreitol (DTT) belongs to the first group whereas the protein kinases inhibitor staurosporine acts on mitochondria. Since the endoplasmic reticulum and the mitochondrial pathways of apoptosis may converge in common steps ...
CUSINATO, FEDERICO, PIGHIN, ISABELLA, LUCIANI, SISTO, TREVISI, LUCIA   +3 more
openaire   +3 more sources

Absence of antimycobacterial synergism between garlic extract and antituberculosis drugs

Diagnostic Microbiology and Infectious Disease, 1987
Garlic extract inhibited the growth of four strains of Mycobacterium tuberculosis, three strains of Mycobacterium avium-intracellulare, and three strains of Mycobacterium kansasii in concentrations ranging from 0.98 mg/ml to 2.94 mg/ml. Synergism could not be demonstrated when garlic extract was added to various concentrations of four commonly used ...
Edward C. Delaha, Vincent F. Garagusi, Mark R. Abbruzzese   +2 more
openaire   +3 more sources

Evaluation of the effect of cavitation activity on drug-ultrasound synergisms

1993 Proceedings IEEE Ultrasonics Symposium, 1993
The authors investigated the effect of therapeutic ultrasound (1 MHz; 0.5-4 W/cm2) on mammalian cells grown in culture in an exposure system that allowed measurement of sub-harmonic generation. They were able to correlate subharmonic generation in the cell samples, a signature of acoustic cavitation, with cell lysis.
R.J. Jeffers, R.Q. Feng, P.D., II Morse, J.B. Fowlkes, D. Kessel, C.A. Cain   +5 more
openaire   +2 more sources

Studies on the synergism of some hypotensive drugs with ethanol.

Polish journal of pharmacology and pharmacy, 1976
Synergism of some hypotensive drugs with ethanol was studied for its influence on the central nervous system. A very strong central action of the drugs and ethanol administered simultaneously in subthreshold doses was observed. Intensity of synergism was calculated by comparing the results with the effective doses of each drug administered seperately.
Wilimowski, Marian, Kędzierska, Lidia, Witkowska, Maria, Barczyńska, Jadwiga, Felsztyńska, Jadwiga   +4 more
openaire   +1 more source

Synergizing drug repurposing and target identification for neurodegenerative diseases

Despite dedicated research efforts, the absence of disease-curing remedies for neurodegenerative diseases (NDDs) continues to jeopardize human society and stands as a challenge. Drug repurposing is an attempt to find new functionality of existing drugs and take it as an opportunity to discourse the clinically unmet need to treat neurodegeneration ...
Mehar Sahu, Shrutikirti Vashishth, Neha Kukreti, Ashima Gulia, Ashish Russell, Rashmi K. Ambasta, Pravir Kumar   +6 more
openaire   +2 more sources

Drug Synergism in Antineoplastic Chemotherapy

1964
Abraham Goldin, J. M. Venditti
openaire   +3 more sources

Drug Resistance and Drug Synergism

2014
Richard B. Silverman, Mark W. Holladay
openaire   +1 more source

Synergism with GABAergic drugs in refractory epilepsy

The Lancet, 1994
MartinJ. Brodie, John Paul Leach
openaire   +2 more sources

Statistical analysis of drug combinations for synergism

Pain, 1992
openaire   +3 more sources

DIET AND DRUG SYNERGISM IN TREATMENT OF HYPERCHOLESTEROLEMIA

Nutrition Reviews, 2009
openaire   +2 more sources