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Drug Synergism [PDF]

Science, 1958
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Half-Sandwich Ruthenium Arene Complexes Bearing Clinically Approved Drugs as Ligands: The Importance of Metal-Drug Synergism in Metallodrug Design.

Molecular Pharmaceutics, 2023
A novel strategy in metallodrug discovery today is incorporating clinically approved drugs into metal complexes as coordinating ligands. Using this strategy, various drugs have been repurposed to prepare organometallic complexes to overcome the ...
Chezhiyan Sumithaa, M. Ganeshpandian
semanticscholar   +1 more source

Drug Resistance and Drug Synergism

2014
Richard B. Silverman, Mark W. Holladay
openaire   +2 more sources

Predicting Drug Synergism by Means of Non-Negative Matrix Tri-Factorization

IEEE/ACM Transactions on Computational Biology & Bioinformatics, 2021
Traditional drug experiments to find synergistic drug pairs are time-consuming and expensive due to the numerous possible combinations of drugs that have to be examined.
Pietro Pinoli, G. Ceddia, S. Ceri, M. Masseroli   +3 more
semanticscholar   +1 more source

Drug Synergism in Antineoplastic Chemotherapy

Advances in chemotherapy, 1964
Abraham Goldin, J. M. Venditti
openaire   +4 more sources

Toxic Reactions Due to Drug Synergism and Antagonism

Anesthesia & Analgesia, 1968
Grosshandler Sl, Kampine Jp, Hanschel Eo
openaire   +4 more sources

Computational studies of drug repurposing and synergism of lopinavir, oseltamivir and ritonavir binding with SARS-CoV-2 protease against COVID-19

Journal of Biomolecular Structure and Dynamics, 2020
A novel coronavirus (SARS-CoV-2) has caused a major outbreak in humans all over the world, and it is the latest pandemic in the series of other infectious diseases.
Nisha Muralidharan, Ramasamy Sakthivel, D. Velmurugan, M. Gromiha   +3 more
semanticscholar   +1 more source

Communicating Synergism in Drug Combination Studies

Arzneimittelforschung, 2011
Isobolograms are used to identify synergistic effects of drugs given in combination. However, the traditional isobologram provides only a qualitative determination of synergism. The present report describes two procedures for quantifying the synergistic actions of drugs based on isobolographic plots.
Harlan E. Shannon, Jesse Brodkin
openaire   +3 more sources

Sequential Blockage as a Theoretical Basis for Drug Synergism

Journal of Medicinal Chemistry, 1963
M. L. Black
openaire   +4 more sources

Synergism in Drug Treatment of Familial Hypercholesterolemia [PDF]

, 1980
The monogenic disorder familial hypercholesterolemia (FH) is associated with a high risk of premature coronary arteriosclerosis, largely attributable to a 2-3 fold increase in levels of low density lipoproteins (LDL) in serum. Heretofore, no regimen of drug therapy or surgical intervention has been reported which is capable of lowering levels of low ...
M. J. Malloy, J. P. Kane, P Tun, R. J. Havel   +3 more
openaire   +1 more source