Results 71 to 80 of about 1,488,693 (165)

An integrative framework for drug target discovery bridging clinical trial and genetic data insights. [PDF]

J Transl Med
Mielke J, Strunz T, Lee J, Schloemer P, GCKD Investigators, Gallone G.   +5 more
europepmc   +1 more source

Temporal trends in evidence supporting novel drug target discovery. [PDF]

Nat Commun
Falaguera MJ, McDonagh EM, Ochoa D, Rusina PV, Roldan-Romero JM, Hulcoop DG, Leach AR, Dunham I.   +7 more
europepmc   +1 more source

Learnable protein representations in computational biology for predicting drug-target affinity. [PDF]

J Cheminform
Kumar R, Romano J, Ritchie M.
europepmc   +1 more source

Menopausal hormone therapy and risk of neuropsychiatric disease: a drug target Mendelian randomisation study. [PDF]

NPJ Womens Health
Schindler LS, Gill D, Oppenheimer H, Barth C, Andreassen OA, Draganski B, Westlye LT, Topiwala A, de Lange AG.   +8 more
europepmc   +1 more source

Structure-free drug-target affinity prediction using protein and molecule language models. [PDF]

J Cheminform
Bidgoli AH, Mahdavi M, Malek H.
europepmc   +1 more source

In silico methods for drug-target interaction prediction. [PDF]

Cell Rep Methods
Ru X, Xu L, Han W, Zou Q.
europepmc   +1 more source

Validation of solvent proteome profiling for antimalarial drug target deconvolution. [PDF]

Int J Parasitol Drugs Drug Resist
Ji Y, Morrow JP, MacRaild CA, Zhang H, Giannangelo C, Schittenhelm RB, Creek DJ, Siddiqui G.   +7 more
europepmc   +1 more source

Aminopeptidase M17 in bacteria: insights into structure, function, and potential as a drug target. [PDF]

J Bacteriol
Askar H, Chen S, Hao H, Jin X, Adel Baz A, Lan S, Li Z, Chu Y.   +7 more
europepmc   +1 more source

Deep Learning-Enabled Multi-Omics Integration: A New Frontier in Precise Drug Target Discovery. [PDF]

Biology (Basel)
Ren Y, Bai H, Wang J, Yang Y, Wang Y.
europepmc   +1 more source

Leveraging multimodal learning for enhanced drug-target interaction prediction. [PDF]

Front Pharmacol
Chen G, Sun K.
europepmc   +1 more source