Results 181 to 190 of about 1,512,902 (358)

Prediction of Novel Drug Targets and Vaccine Candidates against Human Lice (Insecta), Acari (Arachnida), and Their Associated Pathogens [PDF]

, 2021
Abid Ali, Shabir Ahmad, Pedro Machado Medeiros de Albuquerque, Atif Kamil, Fahdah Ayed Alshammari, Abdulaziz Alouffi, Itabajara da Silva Vaz   +6 more
openalex   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

Development of a Peptide-Based Photoimmunotherapy Drug Targeting PD-L1. [PDF]

Molecules
Otani T, Kondo N, Kanai A, Hanaoka H.
europepmc   +1 more source

A review on flavones targeting serine/threonine protein kinases for potential anticancer drugs

, 2019
Lulu Zhao, Xinyu Yuan, Jubo Wang, Yifan Feng, Fei Ji, Zhiyu Li, Jinlei Bian   +6 more
openalex   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Iron oxide nanoparticles in magnetic drug targeting and ferroptosis-based cancer therapy. [PDF]

Med Rev (2021), 2023
Shubhra QTH.
europepmc   +1 more source

Development and Evaluation of Targeted Drug Delivery Systems of Tenoxicam TDDS Prepared With Solid Dispersions

, 2022
Dr. K. Satya Lakshmi
openalex   +2 more sources

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

Molecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard, Sarmad Mehmood, Eva Boysen Fynboe Ebert, Peter Meldgaard, Anindya Dutta, Boe S. Sorensen   +5 more
wiley   +1 more source

Influence of PEG Molecular Weight on Washout Resistance and Deposition Efficiency of Magnetoresponsive Nanoclusters Under Pulsatile Flow for Magnetic Drug Targeting. [PDF]

Pharmaceuticals (Basel)
Bernad SI, Bernad ES.
europepmc   +1 more source

PSMA-targeted dendrimer as an efficient anticancer drug delivery vehicle for prostate cancer

Anubhav Dhull, Jing Wei, Anunay James Pulukuri, Anu Rani, Rishi Sharma, Nooshin Mesbahi, Hosog Yoon, Emily A. Savoy, Sylvia Xaivong, Kenneth John Goody, Clifford E. Berkman, Boyang Jason Wu, Anjali Sharma   +12 more
openalex   +2 more sources