Inhibition of Wnt/β-catenin increases anti-tumor activity by synergizing with sorafenib in hepatocellular carcinoma. [PDF]
He Y+16 more
europepmc +1 more source
Phenotypic plasticity in a newly established set of EGFR inhibitor‐adapted NSCLC cell lines during adaptation and in established cell lines. Here, we introduce novel sublines of the EGFR‐mutant non‐small cell lung cancer (NSCLC) cell lines HCC827 and HCC4006 adapted to the EGFR kinase inhibitors gefitinib (HCC827rGEFI2μm, HCC4006rGEFI1μm), erlotinib ...
Tharsagini V. Nanthaprakash+6 more
wiley +1 more source
Liver‐specific lncRNAs associated with liver cancers
Long non‐coding RNAs (lncRNAs) are regulatory molecules with various functions. They are more tissue‐specific than proteins and can be used as potential biomarkers, particularly in cancer diagnostics and prognosis. In this review, we have systematically compiled all lncRNAs with exclusive expression in the human liver, verified their liver specificity ...
Olga Y. Burenina+3 more
wiley +1 more source
Operational considerations of select new treatment recommendations for drug-susceptible and drug-resistant tuberculosis. [PDF]
Wilson JW, Temesgen Z, Gaensbauer JT.
europepmc +1 more source
Semi‐automated hippocampal avoidance whole‐brain radiotherapy planning
Abstract Background Hippocampal avoidance whole‐brain radiotherapy (HA‐WBRT) is designed to spare cognitive function by reducing radiation dose to the hippocampus during the treatment of brain metastases. Current manual planning methods can be time‐consuming and may vary in quality, necessitating the development of automated approaches to streamline ...
Dong Joo Rhee+9 more
wiley +1 more source
Population Pharmacokinetics and Pharmacodynamics with Enterohepatic Recirculation of Co-Medication of Rosuvastatin and Ezetimibe. [PDF]
An H, Shin D.
europepmc +1 more source
Risk analysis of the Unity 1.5T MR‐Linac adapt‐to‐shape workflow
Abstract Background and Purpose The adapt‐to‐shape (ATS) workflow on the Unity MR‐Linac (Elekta AB, Stockholm, Sweden) allows for full replanning including recontouring and reoptimization5. Additional complexity to this workflow is added when the adaptation involves the use of MIM Maestro (MIM Software, Cleveland, OH) software in conjunction with ...
Jiayi Liang+13 more
wiley +1 more source
Treatment of hypothyroidism with levothyroxine plus slow-release liothyronine: a study protocol for a randomized controlled double-blinded clinical trial. [PDF]
Azizi F+10 more
europepmc +1 more source
Log file‐based quality assurance method for respiratory gating system
Abstract Background As medical linear accelerator technology advances, enabling higher dose rate deliveries, hypofractionation regimens has increased. This necessitates respiratory gating systems that synchronize radiation delivery with tumor position, requiring simple rigorous quality assurance (QA) to ensure treatment accuracy and patient safety ...
Wonjoong Cheon+7 more
wiley +1 more source
Exploring the synergistic effects of metformin and doxorubicin loaded chitosan nanoparticles for A549 lung cancer therapy. [PDF]
Nazemiyeh A+6 more
europepmc +1 more source