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Combination Drug Therapy in Psychopharmacology
The Journal of Clinical Pharmacology, 1975The frequency with which a psychotropic agent is used in combination with another drug preparation is emphasized. The authors present an update of the clinical and theoretical knowledge bearing on combination drug therapy in psychopharmacology. Drug combination interactions that enhance clinical efficacy and those that either diminish it or even ...
W E, Thornton, B J, Pray
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Combination Drug Therapy for Familial Combined Hyperlipidemia
Annals of Internal Medicine, 1988To compare the efficacy of gemfibrozil and colestipol with gemfibrozil and lovastatin in patients with familial combined hyperlipidemia.A prospective, randomized trial.An outpatient clinical research center in a tertiary care center.Seventeen patients with familial combined hyperlipidemia documented by studies of first-degree relatives; nine patients ...
C, East, D W, Bilheimer, S M, Grundy
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Fixed Combination Drug Therapy
Drugs, 1982Almost half of all marketed drugs are fixed combination preparations, yet the World Health Organization included only 7 in its list of 240 "essential' drugs. There has been little scientific study of these preparations but much emotion and rhetoric has been expended both for and against them.
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Combination drug therapy for combined hyperlipidemia
Current Cardiology Reports, 1999Combination therapy for hyperlipidemia, especially combined hyperlipidemia, may have advantages over single drug therapy, affording better improvement in lipoprotein risk factors and possibly better prevention of atherothrombotic events. Although preliminary experience has been gained using treatment combinations of niacin with statins, and fibrates ...
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Combination drug–diet therapies for dyslipidemia
Translational Research, 2010Expense, high drug dose, and low compliance to strict dietary therapies are current issues surrounding modern drug- and diet-based lipid-lowering approaches. Furthermore, variable patient outcomes and suboptimal response to both drug and diet therapies are increasingly evident. Therefore, the question arises as to whether more emphasis should be placed
Rideout, Todd C +3 more
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Selective Drug Taking During Combination Antiretroviral Therapy
JAIDS Journal of Acquired Immune Deficiency Syndromes, 2007Objectives: Multidrug therapy is necessary to achieve sustained viral suppression. Discordant adherence to individual components of a multidrug regimen may lead to adverse outcomes. Methods: Antiretroviral-naive patients initiating therapy from 1997 through 2002 were included. Adherence for each antiretroviral was determined using pharmacy refill data.
Lanzafame M +6 more
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Drug Combinations as Rational Antihypertensive Therapy
Archives of Internal Medicine, 1974The goal of antihypertensive therapy is to restore blood pressure to normal with as few side effects as possible. Usually this is best accomplished by skillfully combining two or more drugs in the regimen. A diuretic should be the cornerstone on which the regimen is built; for many patients with mild hypertension, a diuretic will be the only drug ...
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Journal of the American Academy of Child & Adolescent Psychiatry, 1997
Jacquelyn M. Zavodnick +1 more
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Jacquelyn M. Zavodnick +1 more
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Combination drug therapy for dyslipidaemia
Current Opinion in Lipidology, 1993The use of combination therapy with lipid-lowering agents which have complementary effects on lipoprotein metabolism is an important option for the treatment of severe hyperlipoproteinaemia. This review presents a discussion of recent studies of combination therapy set against the background of existing knowledge in this important therapeutic area.
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