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Fixed Combination Drug Therapy

Drugs, 1982
Almost half of all marketed drugs are fixed combination preparations, yet the World Health Organization included only 7 in its list of 240 "essential' drugs. There has been little scientific study of these preparations but much emotion and rhetoric has been expended both for and against them.
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Combination drug therapy for combined hyperlipidemia

Current Cardiology Reports, 1999
Combination therapy for hyperlipidemia, especially combined hyperlipidemia, may have advantages over single drug therapy, affording better improvement in lipoprotein risk factors and possibly better prevention of atherothrombotic events. Although preliminary experience has been gained using treatment combinations of niacin with statins, and fibrates ...
openaire   +2 more sources

Multifunctional Thermosensitive Liposomes Based on Natural Phase-Change Material: Near-Infrared Light-Triggered Drug Release and Multimodal Imaging-Guided Cancer Combination Therapy.

ACS Applied Materials and Interfaces, 2019
Multifunctional theranostic nanoplatforms (NPs) in response to environment stimulations for on-demand drug release are highly desirable. Herein, the near-infrared (NIR)-absorbing dye, indocyanine green (ICG), and the antitumor drug, doxorubicin (DOX ...
Yeneng Dai   +9 more
semanticscholar   +1 more source

Long-term efficacy and safety of moderate-intensity statin with ezetimibe combination therapy versus high-intensity statin monotherapy in patients with atherosclerotic cardiovascular disease (RACING): a randomised, open-label, non-inferiority trial.

The Lancet, 2022
BACKGROUND Drug combinations rather than increasing doses of one drug can achieve greater efficacy and lower risks. Thus, as an alternative to high-intensity statin monotherapy, moderate-intensity statin with ezetimibe combination therapy can lower LDL ...
Byeong‐Keuk Kim   +15 more
semanticscholar   +1 more source

Combination drug–diet therapies for dyslipidemia

Translational Research, 2010
Expense, high drug dose, and low compliance to strict dietary therapies are current issues surrounding modern drug- and diet-based lipid-lowering approaches. Furthermore, variable patient outcomes and suboptimal response to both drug and diet therapies are increasingly evident. Therefore, the question arises as to whether more emphasis should be placed
Rideout, Todd C   +3 more
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Selective Drug Taking During Combination Antiretroviral Therapy

JAIDS Journal of Acquired Immune Deficiency Syndromes, 2007
Objectives: Multidrug therapy is necessary to achieve sustained viral suppression. Discordant adherence to individual components of a multidrug regimen may lead to adverse outcomes. Methods: Antiretroviral-naive patients initiating therapy from 1997 through 2002 were included. Adherence for each antiretroviral was determined using pharmacy refill data.
Lanzafame M   +6 more
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Drug Combinations as Rational Antihypertensive Therapy

Archives of Internal Medicine, 1974
The goal of antihypertensive therapy is to restore blood pressure to normal with as few side effects as possible. Usually this is best accomplished by skillfully combining two or more drugs in the regimen. A diuretic should be the cornerstone on which the regimen is built; for many patients with mild hypertension, a diuretic will be the only drug ...
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COMBINED DRUG THERAPY DEBATE

Journal of the American Academy of Child & Adolescent Psychiatry, 1997
Jacquelyn M. Zavodnick   +1 more
  +4 more sources

Combination drug therapy for dyslipidaemia

Current Opinion in Lipidology, 1993
The use of combination therapy with lipid-lowering agents which have complementary effects on lipoprotein metabolism is an important option for the treatment of severe hyperlipoproteinaemia. This review presents a discussion of recent studies of combination therapy set against the background of existing knowledge in this important therapeutic area.
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Combined drug therapy of hypertension

1960
Since current drug treatment of hypertension is primarily suppressive rather than curative, the prolonged maintenance of blood pressure reduction is as important as the ability to cause an early and marked depression of the blood pressure by acute treatment.
S. W. Hoobler, P. Lauwers
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