Results 271 to 280 of about 5,099,978 (377)

Altered serine metabolism promotes drug tolerance in <i>Mycobacterium abscessus</i> via a WhiB7-mediated adaptive stress response. [PDF]

Antimicrob Agents Chemother
Bernard C, Liu Y, Larrouy-Maumus G, Guilhot C, Cam K, Chalut C.   +5 more
europepmc   +1 more source

Targeting USP13-mediated drug tolerance increases the efficacy of EGFR inhibition of mutant EGFR in non-small cell lung cancer. [PDF]

Int J Cancer, 2021
Giron P, Eggermont C, Noeparast A, Vandenplas H, Teugels E, Forsyth R, De Wever O, Aza-Blanc P, Gutierrez GJ, De Grève J.   +9 more
europepmc   +1 more source

Ape1 guides DNA repair pathway choice that is associated with drug tolerance in glioblastoma [PDF]

, 2017
Thomas Ströbel, Sibylle Madlener, Serkan Tuna, Sarah Vose, Tonny Lagerweij, Thomas Würdinger, Klemens Vierlinger, Adelheid Wöhrer, Brendan D. Price, Bruce Demple, Okay Saydam, Nurten Saydam   +11 more
openalex   +1 more source

H2O2‐Generating Advanced Nanomaterials for Cancer Treatment

Advanced Functional Materials, EarlyView.
H2O2‐generating nanoplatforms can exploit tumor redox imbalance for O2 and toxic reactive oxygen species generation, leading to hypoxia reversal, and apoptosis of cancer cells, respectively. This review highlights the mechanisms of these nanoplatforms, including exogenous H₂O₂ delivery, endogenous amplification, and metal peroxides, which leads to ...
Kiyan Musaie, Samin Abbaszadeh, Kik Marais, Vahideh Nosrati‐Siahmazgi, Saman Rezaei, Bo Xiao, Kamal Dua, Hélder A. Santos, Mohammad‐Ali Shahbazi   +8 more
wiley   +1 more source

Mesenchymal Stem Cells Increase Drug Tolerance of A431 Cells Only in 3D Spheroids, Not in 2D Co-Cultures. [PDF]

Int J Mol Sci
Vajda F, Szepesi Á, Erdei Z, Szabó E, Várady G, Kiss D, Héja L, Német K, Szakács G, Füredi A.   +9 more
europepmc   +1 more source

Low distress tolerance predicts heightened drug seeking and taking after extended abstinence from cocaine self‐administration [PDF]

, 2017
Travis M. Moschak, Douglas R. Terry, Stacey B. Daughters, Regina M. Carelli   +3 more
openalex   +1 more source

Strategies to Design and Optimize Artificial Antigen‐Presenting Cells for T Cell Expansion in Cancer Immunotherapy

Advanced Functional Materials, EarlyView.
This review highlights recent advances in engineering artificial antigen‐presenting cells (aAPCs) as alternatives to dendritic cells for T cell expansion. Key design principles inspired by the immunological synapse are discussed, with emphasis on strategies for polyclonal and antigen‐specific T cell expansion.
Nguyen Thi Nguyen, Yu Seok Youn
wiley   +1 more source

Pharmacologic Targeting of Histone H3K27 Acetylation/BRD4-dependent Induction of ALDH1A3 for Early-phase Drug Tolerance of Gastric Cancer. [PDF]

Cancer Res Commun
Lee J, Mashima T, Kawata N, Yamamoto N, Morino S, Inaba S, Nakamura A, Kumagai K, Wakatsuki T, Takeuchi K, Yamaguchi K, Seimiya H.   +11 more
europepmc   +1 more source

The Alternative Sigma Factors SigE and SigB Are Involved in Tolerance and Persistence to Antitubercular Drugs [PDF]

, 2017
Davide Pisu, Roberta Provvedi, Dulce Mata Espinosa, Jorge Barrios Payán, Francesca Boldrin, Giorgio Palù, Rogelio Hernández‐Pando, Riccardo Manganelli   +7 more
openalex   +1 more source

Adaptive Chromatin Remodeling Drives Glioblastoma Stem Cell Plasticity and Drug Tolerance.

Cell Stem Cell, 2017
Brian B Liau, C. Sievers, Laura Donohue, Shawn M. Gillespie, William A. Flavahan, Tyler E. Miller, A. Venteicher, Christine H Hebert, Christopher D. Carey, S. Rodig, S. Shareef, Fadi J. Najm, Peter van Galen, H. Wakimoto, D. Cahill, J. Rich, J. Aster, M. Suvà, Anoop P. Patel, B. Bernstein   +19 more
semanticscholar   +1 more source