Severe cutaneous drug toxicity following enfortumab vedotin treatment for metastatic urothelial carcinoma. [PDF]
Enescu CD, Artz C, Axelson A.
europepmc +1 more source
Current and Future Cornea Chip Models for Advancing Ophthalmic Research and Therapeutics
This review analyzes cornea chip technology as an innovative solution to corneal blindness and tissue scarcity. The examination encompasses recent developments in biomaterial design and fabrication methods replicating corneal architecture, highlighting applications in drug screening and disease modeling while addressing key challenges in mimicking ...
Minju Kim+3 more
wiley +1 more source
The Selective Toxicity of Antimicrobial Nitroheterocyclic Drugs
David Edwards, M. H. Dye, H. R. Carne
openalex +1 more source
Race and Drug Toxicity: A Study of Three Cardiovascular Drugs with Strong Pharmacogenetic Recommendations. [PDF]
O'Brien TJ+4 more
europepmc +1 more source
Extracellular vesicles (EVs) play a dual role in diagnostics and therapeutics, offering innovative solutions for treating cancer, cardiovascular, neurodegenerative, and orthopedic diseases. This review highlights EVs’ potential to revolutionize personalized medicine through specific applications in disease detection and treatment.
Farbod Ebrahimi+4 more
wiley +1 more source
Establishment of a human 3D in vitro liver-bone model as a potential system for drug toxicity screening. [PDF]
Chen G+10 more
europepmc +1 more source
Synthetic cells (SCs) hold great promise for biomedical applications, but manual production limits scalability. This study presents an automated method for large‐scale SC synthesis, integrating robotic liquid handling and machine learning‐driven high‐throughput characterization.
Noga Sharf‐Pauker+7 more
wiley +1 more source
Serial transplantation of methotrexate-resistant bone marrow: protection of murine recipients from drug toxicity by progeny of transduced stem cells [PDF]
CA Corey+3 more
openalex +1 more source
Explainable artificial intelligence (XAI) to find optimal in-silico biomarkers for cardiac drug toxicity evaluation. [PDF]
Pramudito MA+4 more
europepmc +1 more source