Results 231 to 240 of about 5,373,155 (364)

Generation of Tetrafluoroethylene-Propylene Elastomer-Based Microfluidic Devices for Drug Toxicity and Metabolism Studies. [PDF]

ACS Omega, 2021
Sano E, Deguchi S, Matsuoka N, Tsuda M, Wang M, Kosugi K, Mori C, Yagi K, Wada A, Yamasaki S, Kawai T, Yodogawa M, Mizuguchi H, Nakazawa N, Yamashita F, Torisawa YS, Takayama K.   +16 more
europepmc   +1 more source

Toward Design Principles for Biomolecular Condensates for Metabolic Pathways

Advanced Biology, EarlyView.
Biomolecular condensates are membrane‐less compartments found through‐out nature which can serve as reaction crucibles for biochemical processes. This review explores the design strategies underlying how condensates can be used in biotechnology to enhance multistep enzyme cascades including enhancement by mass action and substrate channeling, and ...
Alain A.M. André, Nikita Rehnberg, Ankush Garg, Magnus Kjærgaard   +3 more
wiley   +1 more source

Ethanol induced inhibition of hepatic first-pass elimination of mesantoin (M) — A model for ethanol related drug toxicity

, 1978
J Bircher, Thomas Zysset, R Preisig
openalex   +1 more source

Redox Cycling of Radical Anion Metabolites of Toxic Chemicals and Drugs and the Marcus Theory of Electron Transfer [PDF]

, 1990
Ronald P. Mason
openalex   +1 more source

Editorial for the Special Issue: "Feature Papers in Drug Toxicity". [PDF]

Toxics
Sari Y.
europepmc   +1 more source

2-deoxyglucose transiently inhibits yeast AMPK signaling and triggers glucose transporter endocytosis, potentiating the drug toxicity. [PDF]

PLoS Genet, 2022
Laussel C, Albanèse V, García-Rodríguez FJ, Ballin A, Defenouillère Q, Léon S.   +5 more
europepmc   +1 more source

The Regulation of Trace Metal Elements in Cancer Ferroptosis

Advanced Biology, EarlyView.
The induction of ferroptosis inhibits tumor growth, enhances anticancer efficacy, and overcomes drug resistance. Recent evidence shows nonferrous metal elements play a role in ferroptosis. This review focuses on how trace metals regulate ferroptosis processes like iron accumulation, lipid peroxidation, and antioxidant defense.
Xiaoyan Wang, Yuanyuan Xue, Lei Chang, Xuena Zhu, Wenjun Liu, Tingbo Liang   +5 more
wiley   +1 more source

Drug metabolism and the mechanism for appearance of toxicity (9). New findings on acetaminophen

, 1978
Keiko Kobayashi, Kazuo Aikawa, Tetsuo Satoh, Haruo Kitagawa, Masayoshi Kanisawa   +4 more
openalex   +1 more source

Nonsteroid drug selectivities for cyclo-oxygenase-1 rather than cyclo-oxygenase-2 are associated with human gastrointestinal toxicity: A full in vitro analysis [PDF]

, 1999
Timothy D. Warner, Francesco Giuliano, Ivana Vojnovic, Antoaneta Bukasa, Jane A. Mitchell, John R. Vane   +5 more
openalex   +1 more source

Chronic disease diagnoses and health service use among people who died of illicit drug toxicity in British Columbia, Canada. [PDF]

BMC Med
Palis H, Hu K, Tu A, Scheuermeyer F, Staples JA, Moe J, Haywood B, Desai R, Xavier CG, Xavier JC, Crabtree A, Slaunwhite A.   +11 more
europepmc   +1 more source