Results 21 to 30 of about 6,137,811 (297)
Journal of Cardiovascular Development and Disease, 2023 Multiple sclerosis (MS) is a chronic neurological disorder characterized by inflammation in the central nervous system (CNS) that leads to neurodegeneration. The clinical course is highly variable, but its prevalence is rising worldwide, partly thanks to
Matteo Zavarella +4 more
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Anti-epileptic drug toxicity in children [PDF]
, 2018 Anti-epileptic drugs (AEDs) have had a major impact on children, improving their quality of life and significantly reducing both morbidity and mortality. They are, however, associated with significant toxicity. Behavioural problems and somnolence are the
Choonara, Imti
core +3 more sources
An Update on the Relationship of SARS-CoV-2 and Male Reproduction
Frontiers in Endocrinology, 2021 Since the outbreak of the COVID-19, up to now, infection cases have been continuously rising to over 200 million around the world. Male bias in morbidity and mortality has emerged in the COVID-19 pandemic. The infection of SARS-CoV-2 has been reported to
Juncen Guo +9 more
doaj +1 more source
Chronotoxici-Plate Containing Droplet-Engineered Rhythmic Liver Organoids for Drug Toxicity Evaluation. [PDF]
Adv Sci (Weinh)Zhou J +10 more
europepmc +3 more sources
Uniplanar nystagmus associated with perceptual and cognitive visual dysfunction due to presumed focal ischemic occipital cortical atrophy: a missed diagnosis and new observation [PDF]
, 2012 Uniplanar nystagmus has been described in relation to pathology of the brain stem, retina, optic nerve, sensory visual deprivation, periventricular leucomalacia, and drug toxicity.
Dorris, Liam +2 more
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Role of gemcitabine in the treatment of advanced and metastatic breast cancer [PDF]
, 2003 Gemcitabine is an antimetabolite drug with proven antitumor activity and tolerability in metastatic breast cancer. In a total of nine studies, gemcitabine monotherapy has reached response rates of up to 37% in the first-line setting, 26% in the second ...
Heinemann, Volker
core +1 more source
, 1998 Acneiform dermatoses are follicular eruptions. The initial lesion is inflammatory, usually a papule or pustule. Comedones are later secondary lesions, a sequel to encapsulation and healing of the primary abscess.
Jansen, Thomas, Plewig, G.
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Clinical and Translational Science, 2020 Liver microphysiological systems (MPSs) are promising models for predicting hepatic drug effects. Yet, after a decade since their introduction, MPSs are not routinely used in drug development due to lack of criteria for ensuring reproducibility of ...
Andrés Rubiano +14 more
semanticscholar +1 more source
Trends and characteristics of accidental and intentional codeine overdose deaths in Australia [PDF]
, 2015 Examines trends in codeine-related mortality rates in Australia, and the clinical and toxicological characteristics of codeine-related deaths. Abstract Objectives: To examine trends in codeine-related mortality rates in Australia, and the clinical and ...
Amanda Roxburgh +6 more
core +1 more source
PARP inhibitors combined with radiotherapy: are we ready?
Frontiers in Pharmacology, 2023 PARP was an enzyme found in the nucleus of eukaryotic cells that played a crucial role in repairing damaged DNA. Recently, PARP inhibitors have demonstrated great potential in cancer treatment.
Chen Sun +6 more
doaj +1 more source