Results 111 to 120 of about 333,697 (260)
Advanced Science, EarlyView.An autologous whole‐tumor‐cell vaccine (rWTC‐MBTA) is evaluated in murine CNS lymphoma. Subcutaneous vaccination activates dendritic cells, broadens T‐cell priming, and drives lymphocyte trafficking to brain tumors, producing durable tumor control. Longitudinal bioluminescence and adoptive‐transfer assays verify CNS engagement. Combination with anti‐PD‐
Yaping Zhang +10 more
wiley +1 more source
Assessing the Counterfactual: The Efficacy of Drug Interdiction Absent Racial Profiling [PDF]
, 2005 This Article investigates the costs and benefits of racial profiling in the context of drug interdiction. I begin by reviewing the empirical economic and civil rights literature regarding the existence and rationality of racial profiling and then build ...
Barnes, Katherine Y.
core +1 more source
Advanced Science, EarlyView.Chronic septic arthritis involves intracellular bacterial persistence and lipid‐immune crosstalk via the PGRN‐BMP lysosomal axis. A dual‐targeting nanoparticle system (NPs@PGRN) restores lysosomal bactericidal function, reduces bacterial burden, and reprograms macrophage immunity, offering a novel therapeutic strategy. ABSTRACT Chronic septic arthritis,
Congsun Li +12 more
wiley +1 more source
Spartan Daily, August 31, 1983 [PDF]
, 1982 Volume 81, Issue 3https://scholarworks.sjsu.edu/spartandaily/7053/thumbnail ...
San Jose State University, School of Journalism and Mass Communications
core +3 more sources
Endocytic Control of Cell‐Autonomous and Non‐Cell‐Autonomous Functions of p53
Advanced Science, EarlyView.NUMB Ex3‐containing isoforms localize to the plasma membrane, where they recruit p53 through SNX9 and direct it to multivesicular bodies and exosomes. Exported p53 is taken up by neighboring cells and activates nuclear programs, revealing an intercellular, exosome‐based pathway that might help establish a tumor‐suppressive microenvironment.
Roberta Cacciatore +20 more
wiley +1 more source
Advanced Science, EarlyView.This work develops dynamically softening polyacrylamide hydrogels for time‐resolved imaging during continuous mechanical transitions. The study revealed that mechanotransduction is biphasic; YAP/TAZ inactivation is driven by early loss of the nucleocytoskeletal continuum connecting subnuclear adhesions, F‐actin, and the nuclear envelope, coupled with ...
Alessandro Gandin +12 more
wiley +1 more source
Drivers’ Knowledge, Attitude and Practices Towards Traffic Rules and Regulations
Journal of Road SafetyResearch frequently reports that the majority of crashes (up to 80%), are the fault of drivers. Further, the WHO reports that most fatal crashes occur in low- and middle-income countries (LMIC).
Sheer Abbas +3 more
doaj +1 more source
Association between Substance Abuse and Road Traffic Accidents in Iraq
Journal of Forensic Science and MedicineBackground: The relationship between substance abuse and traffic accidents is an ongoing relationship, as it is considered one of the most dangerous global accidents that cause deaths in the world. Aims and Objectives: The aim of the study is to identify
Mahmoud Mohammed Ahmed +2 more
doaj +1 more source