Results 21 to 30 of about 333,697 (260)
"Alternative" endocytic mechanisms exploited by pathogens: new avenues for therapeutic delivery? [PDF]
, 2007 Some pathogens utilize unique routes to enter cells that may evade the intracellular barriers encountered by the typical clathrin-mediated endocytic pathway.
Medina-Kauwe, LK
core +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
How effective is non-custodial sentencing in achieving compliance with road traffic law? [PDF]
, 2012 This paper was presented at the Achieving Compliance with Road Traffic Law: What can enforcement, prosecution and sentencing contribute? Conference hosted at Brunel University on the 13th June 2012.As we are all aware, the vast majority of road traffic ...
Easton, S, Piper, CD
core
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
A Budding Theory of Willful Patent Infringement: Orange Books, Colored Pills, and Greener Verdicts [PDF]
, 2007 The rules of engagement in the brand-name versus generic-drug war are rapidly changing. Brand-name manufacturers face increasing competition from Canadian manufacturers of generic drugs, online drug companies, and Wal-Mart® Super Centers deciding to cash
Harkins, Christopher A.
core +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
The determination of non-alcoholic substance use in drivers: Why? How? Where?
Psychiatry and Clinical Psychopharmacology, 2021 This article describes the background, legislations and new approaches in Turkey for control of drug use of drivers. In recent years, in parallel to the widespread use of illicit drugs, the number of drivers affected by drugs is also increasing.
Serap A. Akgür +3 more
doaj
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Annual performance indicators of enforced driver behaviours in South Australia, 2007 [PDF]
, 2009 This report was produced to quantify performance indicators for selected enforced driver behaviours (drink driving, drug driving, speeding and restraint use) in South Australia for the calendar year 2007. The level of random breath testing (RBT) in South
Baldock, M. +2 more
core
Vehicle-related crime and the gender gap [PDF]
, 2007 Although vehicle-related offending and traffic offenders are of interest to some behavioural psychologists, criminologists have been less enthused and their concern has been largely restricted to crime to vehicles rather than crime by drivers or wider ...
Corbett, C
core +2 more sources