Results 31 to 40 of about 132,064 (306)
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
‘You want to chill with the big boys’: Proverbs 21:4–7 and drug trafficking in Nigeria
Verbum et Ecclesia, 2022 Although progress has been made in the study of Proverbs 21:4–7, existing literature is yet to shift focus on the relevance of the pericope in examining the different aspects of drug trafficking by Nigerians.
Favour C. Uroko, Success A. Nnadi
doaj +1 more source
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
A Sociological Approach to Drug Use
EIRP Proceedings, 2021 Lately, the illicit drug market in Romania has shown a continuous dynamics, registering an increase both in the availability of most types of drugs consumed and in the total amount of drugs confiscated, especially cocaine and cannabis. The availability
Angela-Mihaela Ene
doaj
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
The Drug-Trafficking Economy and Its Dynamics in Latin America
Íconos, 2013 This article analyzes the behavior of drug-trafficking economy in Latin America during the last twelve years and its influence in the configuration of a new crime scenario in the region.
Daniel Pontón C.
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Theoretical and practical aspects of preventive work in the fight against drug addiction
Вестник Тамбовского университета. Серия: Гуманитарные науки, 2020 The aim of the work is to study the theoretical and practical aspects of the emergence of drug addiction, types of preventive work in the fight against drug addiction, the peculiarities of its spread among adolescents. An assessment of the development of
Y. V. Platonova +3 more
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Challenges and prospects of an absent methodology
Sortuz, 2023 The present paper seeks to analyze treaties and national laws aimed at protecting victims and criminalizing the perpetrators on the topics of international drug trafficking and trafficking in persons, as well as highlight the gender vulnerability ...
Izabela Zonato Villas Boas +1 more
doaj +1 more source
The role of lipid metabolism in neuronal senescence
FEBS Open Bio, EarlyView.Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari +2 more
wiley +1 more source