Results 161 to 170 of about 2,255,889 (297)

FXR and Nrf2 Mediate the Effect of Carbon Ion Irradiation on Drug Transporter OATP1A2 in Cancer Cells. [PDF]

Biology (Basel)
Li Z, Zhang Z, Li Z, Yuan J, Du Y, Hong M.   +5 more
europepmc   +1 more source

Characterization of a P-glycoprotein drug transporter from Toxocara canis with a novel pharmacological profile. [PDF]

Int J Parasitol Drugs Drug Resist, 2021
Jesudoss Chelladurai JRJ, Jones DE, Brewer MT.   +2 more
europepmc   +1 more source

A Holistic Platform Approach for Developing Robust Pulmonary mRNA Delivery: Integrating Novel Phenolic Acid‐Derived Ionizable Lipids and Device Engineering

Advanced Functional Materials, EarlyView.
An integrated pulmonary mRNA delivery platform combining novel biodegradable syringic acid‐derived ionizable lipids, design‐of‐experiments formulation optimization, and vibrating‐mesh nebulizer engineering enabled stable aerosolization and efficient lung delivery.
Neha Kaushal, Younan Ma, Asad Khanmohammed, Dipen Parande, Hanming Zhang, Saket Dolare, Juliet Chen, Apiwat Wangweerawong, Saswata Karmakar, Hongfeng Deng, Frank Koppenhagen, Shraddha Sharma, Eric Reyes, Sherry He, Lianne Boeglin, Caroline Woo, Azadeh Paksa, Ayed Allawzi, Anusha Dias, Gregory Troiano, Shrirang Karve, Frank DeRosa   +21 more
wiley   +1 more source

ABC Transporter Blockers and Reversal of Drug Resistance in Microorganisms.

, 2012
One of the major causes of drug resistance and chemotherapeutic failure in both cancer and anti-infective therapies is the decrease of effective drug concentrations at their target place, due to the increased action of ATP-binding cassette (ABC ...
Ponte-Sucre, Alicia, Diaz, Emilia, Padron-Nieves, Maritza   +2 more
core  

Influence of inflammation on drug transporter expression in human airway epithelia: Implications for inhaled drug pharmacokinetics. [PDF]

Drug Metab Dispos
Esther CR, Fallon JK, Cholon DM, Boyles SE, Williams AB, Murano H, Okuda K, Tiley JB, Tan ML, Zhao L, Mikami Y, Smith PC, Rao G, Gentzsch M.   +13 more
europepmc   +1 more source

VARIDT 1.0: variability of drug transporter database. [PDF]

Nucleic Acids Res, 2020
Yin J, Sun W, Li F, Hong J, Li X, Zhou Y, Lu Y, Liu M, Zhang X, Chen N, Jin X, Xue J, Zeng S, Yu L, Zhu F.   +14 more
europepmc   +2 more sources

ZIKV Disrupts Placental Ultrastructure and Drug Transporter Expression in Mice. [PDF]

Front Immunol, 2021
Andrade CBV, Monteiro VRS, Coelho SVA, Gomes HR, Sousa RPC, Nascimento VMO, Bloise FF, Matthews SG, Bloise E, Arruda LB, Ortiga-Carvalho TM.   +10 more
europepmc   +1 more source

An Epigenetic Fate Converter Based on Nuclei‐Targeting Lipid Nanoparticles Drives Neuronal Programming of Stem Cells for Spinal Cord Repair

Advanced Functional Materials, EarlyView.
Schematic illustration of LNP‐MPG nuclei‐targeting delivery of HMW‐FGF2 promoting histone acetylation to regulate the fate of DPSCs and treat spinal cord injury. LNPs components include pHMW‐FGF2 plasmid, DSPC, Dlin‐MC3‐DMA, cholesterol, and PEG2000, and are modified with MPG to form HMW‐FGF2@LNP‐MPG (HLM). HLM nuclei‐targets DPSCs to deliver HMW‐FGF2,
Heng Zhou, Qiang Qin, Xiqin Li, Hanyu Ding, Chun Xu, Yan He, Qingsong Ye   +6 more
wiley   +1 more source

Potential Links Between Aging, Mitochondrial Dysfunction, and Drug Transporter Function-Molecular Mechanisms and Pharmacokinetic Implications. [PDF]

Int J Mol Sci
Rzeczycki P, Pęciak O, Plust M, Droździk M.   +3 more
europepmc   +1 more source

Fetal glucocorticoid exposure leads to sex-specific changes in drug-transporter function at the blood-brain barrier in juvenile guinea pigs. [PDF]

FASEB J, 2022
Eng ME, Bloise E, Matthews SG.
europepmc   +1 more source