Results 181 to 190 of about 18,584,597 (312)

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

Drug Use Among University Students in Pakistan: A Public Health Concern. [PDF]

Subst Abuse Rehabil
Fareed A, Ashraf T, Mujtaba G.
europepmc   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Distinguishing a drug use disorder from drug use in a high-risk sample of youth: A random forest classification and explanatory analysis. [PDF]

Drug Alcohol Depend Rep
Berny LM, Guha A, Tanner-Smith EE.
europepmc   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Prescription Drug Use Among US Adults.

JAMA Netw Open
Monroy-Iglesias MJ, Wang P, Sampathkumar Y, O'Connell K, Chan AT, Du M, Haas JS, Giovannucci EL, Kantor ED.   +8 more
europepmc   +1 more source

Time Windows Used When Identifying Current Drug Use and Polypharmacy. [PDF]

Pharmacoepidemiol Drug Saf
Giometto S, Reilev M, Ernst MT, Støvring H, Pottegård A.   +4 more
europepmc   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Long-Term Outcomes With Class 1C Antiarrhythmic Drug Use in Atrial Fibrillation. [PDF]

J Am Heart Assoc
Bhonsale A, Wang Y, Thoma F, Kancharla K, Voigt A, Shalaby A, Naniwadekar A, Singla V, Estes NA, Saba S, Mulukutla S, Jain S.   +11 more
europepmc   +1 more source

Use and Abuse of Drugs [PDF]

BMJ, 1965
openaire   +2 more sources