Results 201 to 210 of about 5,252,361 (312)

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

Molecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen, Jiancheng Cheng, Ruili Hou, Xiaoyuan Zheng, Li Su, Maria Moksnes Bjaanæs, Anna Karlsson, Maria Planck, Johan Staaf, Åslaug Helland, Manel Esteller, David C. Christiani, Feng Chen, Xiaofei Cao, Ruyang Zhang   +14 more
wiley   +1 more source

Clinical Manifestations of Subjects with Long COVID and Their Associations with Drug Use: The BioICOPER Study. [PDF]

Biomedicines
Arroyo-Romero S, Gomez-Sanchez L, Suarez-Moreno N, Navarro-Caceres A, Dominguez-Martin A, Lugones-Sanchez C, Gonzalez-Sanchez S, Gomez-Sanchez M, Rodriguez-Sanchez E, Garcia-Ortiz L, Navarro-Matias E, Gomez-Marcos MA.   +11 more
europepmc   +1 more source

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

Molecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy, Jana Löptien, Cornelia Coith, Afroditi Nanou, Katharina Hintelmann, Pinnschmidt Hans, Cordula Petersen, Klaus Pantel, Sabine Riethdorf, Kerstin Borgmann, Harriet Wikman   +10 more
wiley   +1 more source

The Earned Income Tax Credit and short-term changes in financial strain and drug use. [PDF]

Health Aff Sch
Gutkind S, Wall MM, Keyes KM, Martins SS, Hasin DS.   +4 more
europepmc   +1 more source

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

FEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz, Bruna Abreu, Cindy Mendes, Catarina Freitas‐Dias, Filipe Gonçalves, Fernanda Silva, José Ramalho, Saudade André, Vasco D. B. Bonifácio, Jacinta Serpa   +9 more
wiley   +1 more source

Effects of age and drug use on lower gastrointestinal bleeding: a retrospective single-center experience. [PDF]

BMC Gastroenterol
Onem S, Güven İE, Derebey M, Arayici ME, Dolu S.   +4 more
europepmc   +1 more source

Down‐regulation of Shh in the hair follicles of mice during chemotherapy‐induced hair loss is mediated by the JAK/STAT1 signaling pathway

FEBS Open Bio, EarlyView.
We found that during chemotherapy‐induced alopecia (CIA), Sonic hedgehog (Shh) expression significantly decreased in hair follicle Shh+ cells, whereas the Janus‐activated kinase/signal transducer and activator of transcription 1 (JAK/STAT1) signaling pathway was markedly activated.
Ruifang Fan, Jingling Huang, Xiang Lin, Tingjiao Lan, Yuli Tang, Ling Sun, Guixuan Zhou   +6 more
wiley   +1 more source

Z-Drug Use and All-Cause Mortality: A Meta-Analysis of Observational Cohort Studies. [PDF]

Neuropsychiatr Dis Treat
Park JY, Park HJ, Ko HJ, Kim AS, Song JE, Hong HE.   +5 more
europepmc   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

Prognostic Impact of Recreational Drug Use on 1-Year Outcomes in NSTEMI and STEMI Patients. [PDF]

JACC Adv
Aboujaoude M, Hamache N, Dillinger JG, Trimaille A, Bouleti C, Delmas C, Schurtz G, Houssany-Pissot S, Vasram RR, Bonnet G, Millischer D, Thuaire C, Roubille F, Noirclerc N, Andrieu S, Fauvel C, Mirailles R, Hudelo J, Gonçalves T, Florence J, Unger A, Singh M, Gall E, Lafont A, Toupin S, Menezes L, Vicaut E, Henry P, Pezel T, ADDICT-ICCU Investigators.   +29 more
europepmc   +1 more source