Results 191 to 200 of about 8,164,322 (359)

A Prospective Study of Drug Utilization and Evaluation in Gastrointestinal Disorders at a Tertiary Care Teaching Hospital

Sarfaraz Md, Devkar Aniket, J. Keerthi, B Rajesh, Hiremath Doddayya   +4 more
openalex   +1 more source

Survivin and Aurora Kinase A control cell fate decisions during mitosis

Molecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir, Shalitha Wickrama Arachchige, Sally P. Wheatley   +2 more
wiley   +1 more source

Impact of Supply Chain Disruptions and Drug Shortages on Drug Utilization: A Scoping Review. [PDF]

Pharmacoepidemiol Drug Saf
Santhireswaran A, Chaudhry S, Ho M, Fuller K, Gaudette E, Burry L, Tadrous M.   +6 more
europepmc   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Drug Utilization and Medication Adherence: A Data-Driven Analysis of Drugs with Different Routes of Administration Applied in Atopic Dermatitis. [PDF]

Pharmaceutics
Mucherino S, Raimondo A, Krstin M, Aznar-Lou I, Serino M, Perrella L, Bernardi FF, Trama U, Menditto E, Lembo S, Orlando V.   +10 more
europepmc   +1 more source

Drug utilization study and safety profile of iron isomaltoside 1000 in treatment of iron deficiency anemia in cancer patients: a retrospective study

Davinder Paul, Manish Mahajan, Suyash Bharat, Richa Tripathi   +3 more
openalex   +2 more sources

Influencers of generic drug utilization: A systematic review

Research in Social and Administrative Pharmacy, 2017
Jennifer N Howard, I. Harris, Gavriella Frank, Z. Kiptanui, J. Qian, R. Hansen   +5 more
semanticscholar   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

Drug Utilization, Adherence and Predictors of Drug-Changes and Discontinuation of Glaucoma Drug Therapies. [PDF]

Adv Ther
Novella A, Quaranta L, Pasina L, Galbussera AA, Tettamanti M, Fortino I, Leoni O, Weinreb RN, Nobili A.   +8 more
europepmc   +1 more source

Drug Utilization Evaluation of Erythropoietin at a Referral Teaching Hospital in Iran. [PDF]

Adv Pharmacol Pharm Sci, 2023
Karimzadeh I, Rasekh H, Karimian A, Shabani-Borujeni M, Vazin A.   +4 more
europepmc   +1 more source