Results 101 to 110 of about 412,569 (303)

Pyrrole Alkaloids from the Edible Mushroom Phlebopus portentosus with Their Bioactive Activities

Molecules, 2018
Seven pyrrole alkaloids, three of which are novel (phlebopines A–C (1–3)), were isolated from the fruiting bodies of the edible mushroom Phlebopus portentosus. Their structures were determined on the basis of spectroscopic data.
Zhaocui Sun, Meigeng Hu, Zhonghao Sun, Nailiang Zhu, Junshan Yang, Guoxu Ma, Xudong Xu   +6 more
doaj   +1 more source

Limited Options to Manage Specialty Drug Spending [PDF]

, 2012
Outlines rising trends in costs of and spending on specialty drugs; health plans' efforts to curb specialty drug spending, including patient cost sharing and utilization management; and efforts to integrate medical and pharmaceutical ...
Divya R. Samuel, Ha T. Tu
core  

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Investigation of the rational use of teicoplanin in inpatient wards of teaching hospitals in Birjand, Iran, from 2022 to 2023 [PDF]

مجله دانشگاه علوم پزشکی بیرجند
Background and Aims: Incorrect and excessive use of antibiotics has led to a significant rise in drug resistance. Nowadays, irrational antibiotic use is a major contributor to increased illness, death, and healthcare costs.
Motahareh Mahi-Birjand, Effat Alemzadeh, Saeed Jalalian, Soudabe Es'haghi   +3 more
doaj  

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Evaluation of rational prescription pattern of intravenous immunoglobulin (IVIG) based on FDA-approved indications among teaching hospitals in Birjand

مجله دانشگاه علوم پزشکی بیرجند, 2022
Background and Aims: Intravenous immunoglobulin (IVIG) is one of the safest biological products, which is effective in the treatment of many diseases.
Abolfazl Abbaszadeh, Mohammad Ali Mahdiabadi, Seyed Mohammad Riahi, Razieh Avan   +3 more
doaj  

Willingness to Pay for Community Health Fund Card in Mtwara Rural District,Tanzania [PDF]

, 2003
\ud The Ministry of Health in Tanzania has established a new programme in the primary health care service. CHF is a district-level prepayment scheme targeted at the rural population.CHF starts in 1995 on a pilot basis in one district and in 2003 has to ...
Baraldes, Carme, Carreras , Lluis
core  

Drug utilization evaluation of antibiotics in district hospital Rudraprayag

Journal of Drug Delivery and Therapeutics, 2018
Drug utilization is very important for antibiotics as they are widely used in hospitals and their in appropriate use may lead to resistance. To check this irrational use of antibiotics and promote rational use the present retrospective study was conducted to access drug utilization evaluation of antibiotics in in patient department of District Hospital
Upendra Kumar Jain, Rupinder Kaur Sodhi, Kanishk Kala   +2 more
openaire   +2 more sources

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Evaluation of the clinical application of histamine H2 receptor antagonists in the prevention of chemotherapy-induced nausea and vomiting based on the attribute hierarchy model method

Frontiers in Pharmacology
ObjectiveTo investigate the clinical application of histamine H2 receptor antagonists (H2 RAs) in the prevention of chemotherapy-induced nausea and vomiting (CINV), focusing on the rationality of H2 RAs use, the utilization rates and costs of different ...
Jiawei Song, Li Liu, Bingbing Meng, Huanhuan Zhao, Pengcheng Zhang, Huijuan Chen, Yuanyuan Wang   +6 more
doaj   +1 more source