Results 131 to 140 of about 1,488,766 (342)

Pharmacoepidemiological research of lipid-lowering therapy in ischemic heart disease

open access: yesКубанский научный медицинский вестник, 2014
The pharmacoepidemiological study includes a review of the use of lipid-lowering drugs with the main indicators of consumption - defined daily dose (DDD) and prescribed daily dose (PDD).
M. A. Mishchenko, N. N. Chesnokova
doaj  

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

Impact of supply chain disruptions and drug shortages on drug utilization: A scoping review protocol.

open access: yesPLoS ONE
ObjectiveThis proposed scoping review aims to examine studies assessing the impact of drug shortages on population-level drug utilization trends. The objectives of this review are to a) assess which drugs have been studied and describe associated drug ...
Araniy Santhireswaran   +5 more
doaj   +1 more source

Prospects and Challenges of Medicinal Plants Conservation and\ud Traditional Medicine in Tanzania [PDF]

open access: yes, 2013
A qualitative study was carried to assess prospects and challenges of medicinal plants conservation and\ud traditional medicine in Tanzania. The study shows that TRM and medicinal have great prospects in healthcare\ud delivery worldwide.
Kayombo, Edmund J   +2 more
core  

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Avaliação de prescrições medicamentosas de um hospital universitário brasileiro

open access: yesRevista Brasileira de Educação Médica
A prescrição é o ponto de partida para a utilização de medicamentos. O objetivo deste trabalho foi identificar a qualidade das informações presentes nas prescrições das enfermarias de um hospital universitário brasileiro.
Joice Mara Cruciol-Souza   +2 more
doaj   +1 more source

Costing Artemisinin-based Combination Therapy for Malaria in Tanzania [PDF]

open access: yes, 2005
Malaria continues to be a major contributor to the burden of disease in Tanzania, with a prevalence of 33.39 percent nationally. As antimalarial resistance to sulfadoxine-pyrimethamine in Tanzania continues to grow, the government is in the process of ...
Derriennic, Yann, Wolf, Katherine
core  

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Pharmacovigilance in clinical trials [PDF]

open access: yesVojnosanitetski Pregled, 2007
Ilić Katarina, Ugrešić Nenad
doaj   +1 more source

Costs and Benefits of Elderly Prescription Drug Coverage: Evidence from Veterans’ Health Care [PDF]

open access: yes
This study tests the impact of a public prescription benefit on Medicare-eligible veterans, utilizing a mid-1990s benefit change in the VA health care system.
Melissa Boyle
core  

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