Results 121 to 130 of about 16,766,351 (298)
Качественная клиническая практика, 2018 The article describes the methodology for conducting drug utilization researches that study the sales, distribution and use of drugs in the community, with special attention to the medical, social and economic results.
A. E. Cheberda
doaj
Determinants and Policy Implications of Drug Utilization in the Philippines [PDF]
The drug question has emerged recently, which is the crux of the Philippine health concerns today. While studies on the supply side of pharmaceuticals have been profuse, the demand side seems to be neglected.
Bautista, Cristina
core
Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
Do Drug Plans Matter? Effects of Drug Plan Eligibility on Drug Use Among the Elderly, Social Assistance Recipients and the General Population [PDF]
The 1984 Canada Health Act does not require that the provinces subsidize prescription drugs. Many provinces do, however, provide categorical coverage to the elderly, social assistance recipients and others, although the generosity of coverage is highly ...
Paul V. Grootendorst, Mitchell Levine
core +2 more sources
A Review Drug Utilization and Evaluation of Rabeprazole
International Journal of Advanced Research in Science, Communication and TechnologyRabeprazole is a proton pump inhibitor (PPI) commonly prescribed for gastroesophageal reflux disease (GERD), peptic ulcers, and Zollinger-Ellison syndrome. This study investigates the patterns of drug utilization, efficacy, safety, and rational prescribing of Rabeprazole in a hospital setting.
null Omkarnavnath Salgar +4 more
openaire +1 more source
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
Pharmacovigilance in clinical trials [PDF]
Vojnosanitetski Pregled, 2007 Ilić Katarina, Ugrešić Nenad
doaj +1 more source
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Examination of Priorities for Therapeutic Drug Utilization Review
, 1991 Therapeutic Drug Utilization Review (DUR) is an important component of state-level pharmaceutical assistance ...
Ahern, Frank +5 more
core
Prospecting the protein design landscape
FEBS Letters, EarlyView.This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source