Results 101 to 110 of about 16,766,351 (298)

Optimizing Antifungal Use Through Interdisciplinary Intervention in the Hematology Unit

open access: yesJournal of Fungi
Invasive fungal infections are frequent complications in patients with hematologic malignancies due to immunosuppression and intensive treatments. In Colombia, limited diagnostic availability, heterogeneous prescribing practices, and emerging antifungal ...
Maria Alejandra Caro Flautero   +10 more
doaj   +1 more source

Iron deficiency anaemia

open access: yesRevista Médica del Hospital General de México, 2016
Iron deficiency anaemia is a public health problem that affects all age groups. In Mexico, it is a common cause of morbidity, and accounts for 50% of cases of anaemia worldwide.
G. Barragán-Ibañez   +2 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Quantifying the Silent Selection Pressure: Antimicrobial Stewardship and Gut Microbiome Integrity in the NICU and PICU

open access: yesBiomedicines
Background: Antimicrobial stewardship in Neonatal (NICU) and Pediatric Intensive Care Units (PICUs) is complicated by rapid physiological maturation and the high vulnerability of the developing gut microbiome.
Fauna Herawati   +6 more
doaj   +1 more source

Comparative drug utilization research comparing different patients

open access: yes
Comparative drug utilization research based on patient characteristics provides a significant contribution to the knowledge on use of drugs in the real world.
von Euler, Mia,, Petrović, Ana Tomas,
core   +1 more source

Drug utilization studies among ENT patients in various clinical settings: A comprehensive review [PDF]

open access: yes, 2019
Drug utilization research is thus an all important part of pharmacoepideminology as it explains the extent, nature and determinants of drug exposure. A drug utilization study is a tool for determining the effectiveness of drug use.
Rasool, Shafiqa   +2 more
core   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Benefits of Pharmacist’s Participation on Hospitalist Team

open access: yesActa Medica Iranica, 2016
This study was performed to assess the incidence of medication errors and irrational use of human albumin in two wards of our hospital and also aimed to evaluate the ability of pharmaceutical care center and pharmacists in improving patient care. Albumin
Simin Mahdikhani, Fatemeh Dabaghzadeh
doaj  

Assessment of the Heparin and Enoxaparin Prophylaxis Protocol in Patients Receiving Care at Sina Hospital in Tabriz

open access: yesActa Medica Iranica
Venous thromboembolism (VTE) poses a significant risk to hospitalized patients, accounting for approximately 10% of morbidity cases among this population.
Mahsa Seifi Mansour   +4 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

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