Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
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FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
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Drug utilization research in the area of cancer drugs
, 2016 Increased biological understanding of cancer diseases has resulted in a paradigm shift in the medical treatment of cancer. Despite encouraging advances, most cancer types are still incurable and cancer is the second most common cause of death in ...
Wilking, Ulla, +4 more
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Prevalence of antidepressant use in Brazil: a systematic review with meta-analysis [PDF]
Brazilian Journal of PsychiatryObjectives: To estimate the prevalence of antidepressant use in Brazil. Methods: We conducted a systematic review with searches in MEDLINE, Embase, Scopus, LILACS, and SciELO up to May 2023.
Gustavo Magno Baldin Tiguman +5 more
doaj +1 more source
Teaching Independent Decision-Making Through a Computer-Based Drug Utilization Review Simulation. [PDF]
J Pharm Technol, 2023 Peddi AN, Eukel HN, Meyer BA, Caldas LM.
europepmc +1 more source
Drug Utilization Review Current Status and Relationship to Assuring Quality Medical Care
, 1976 Drug utilization is expected to increase in the years ahead, thereby fostering the use of cost control and quality assurance mechanisms in the form of drug utilization/peer review.
James E. Knoben
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Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Pharmacoepidemiological research of lipid-lowering therapy in ischemic heart disease
Кубанский научный медицинский вестник, 2014 The pharmacoepidemiological study includes a review of the use of lipid-lowering drugs with the main indicators of consumption - defined daily dose (DDD) and prescribed daily dose (PDD).
M. A. Mishchenko, N. N. Chesnokova
doaj
Pharmacists' Perceptions on Safety Alerts of the Drug Utilization Review (DUR) in Electronic Health Records in a Tertiary Healthcare Hospital. [PDF]
Pharmacy (Basel), 2023 Alshehri N, Alanazi A.
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The processes of reform in Victoria’s alcohol and other drug sector, 2011-2014 [PDF]
, 2014 This paper explores issues and concerns related to the 2014 alcohol and other drug sector recommissioning process in Victoria. Overview In mid-2014, the Victorian Alcohol and Drug Association approached the Drug Policy Modelling Program, at the ...
Drug Policy Modelling Program
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