Results 81 to 90 of about 241,889 (264)

Drug utilization studies in Turkiye: A systematic review

Northern Clinics of Istanbul
Drug utilization studies (DUS) provide a framework for drug utilization at the national or targeted population level and important information on unmet medical needs, particularly in assessing the rationality of drug use. We aimed to systematically review DUS conducted in Turkiye.We examined 162 DUS with an accessible full-text, published as "research ...
Akıcı, Ahmet, Havyarimana, Dieudonné, Direnç, Ertan, Aydın, Volkan   +3 more
openaire   +3 more sources

Association Between Individualized Education for Kidney Replacement Therapy Modality Selection and Peritoneal Dialysis Initiation: A Cross‐Sectional Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Peritoneal dialysis (PD) is an established home‐based kidney replacement therapy (KRT), but its uptake remains low in Japan. We evaluated whether individualized education in a dedicated outpatient clinic was associated with the initiation of PD.
Yasuko Ito, Ryuichi Yoshimura, Takaki Yamauchi, Yuta Funakoshi, Hirotaka Sonoda, Seiji Kobayashi, Hiroyuki Terawaki, Takafumi Ito   +7 more
wiley   +1 more source

Optimizing Antifungal Use Through Interdisciplinary Intervention in the Hematology Unit

Journal of Fungi
Invasive fungal infections are frequent complications in patients with hematologic malignancies due to immunosuppression and intensive treatments. In Colombia, limited diagnostic availability, heterogeneous prescribing practices, and emerging antifungal ...
Maria Alejandra Caro Flautero, Maria Camila Rubio, Edgar Fabián Manrique-Hernández, Jeimy Lorena León, Olga Daniela Vega Jiménez, Paola Cristina Álvarez Mantilla, Pilar Rivas-Pinedo, Alejandra Mendoza-Monsalve, Maricel Licht-Ardila, Alexandra Hurtado-Ortiz, Carlos Augusto Solórzano   +10 more
doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Human Albumin Utilization in Patients Admitted to a University-affiliated Hospital in Iran

Journal of Pharmacoeconomics and Pharmaceutical Management, 2018
Background: As an essential human protein and an expensive biological drug, albumin is, in several cases, prescribed without an appropriate indication. This study determined the compatibility of albumin administration with the current standard protocols
Afshin Gharekhani, Hamid Noshad, Soheil Teimouri, Haleh Rezaee, Abasad Gharedaghi, Sepideh Rahigh-Aghsan   +5 more
doaj  

Avaliação de prescrições medicamentosas de um hospital universitário brasileiro

Revista Brasileira de Educação Médica
A prescrição é o ponto de partida para a utilização de medicamentos. O objetivo deste trabalho foi identificar a qualidade das informações presentes nas prescrições das enfermarias de um hospital universitário brasileiro.
Joice Mara Cruciol-Souza, João Carlos Thomson, Douglas Godoy Catisti   +2 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Pharmacovigilance in clinical trials [PDF]

Vojnosanitetski Pregled, 2007
Ilić Katarina, Ugrešić Nenad
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source