Aim: Prescribing drugs during pregnancy needs careful consideration of benefit to the mother and risk to the fetus. Therefore, this study was conducted to evaluate the appropriateness of medications among pregnant women with coexisting illness in a ...
Htet Wai Moe, Sushil Sharma, A K Sharma
doaj +1 more source
Current Status of Prospective Drug Utilization Review [PDF]
The Omnibus Budget Reconciliation Act of 1990 offered the promise that prospective drug utilization review (pDUR) systems would improve the quality of drug prescribing and patient drug use. There is little evidence that this promise has been fulfilled. To the contrary, there is growing evidence that suboptimal use of drugs (in terms of preventable drug-
Thomas R, Fulda +3 more
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Stimulation of glucose utilization in 3T3 adipocytes and rat diaphragm in vitro by the sulphonylureas, glimepiride and glibenclamide, is correlated with modulations of the cAMP regulatory cascade [PDF]
The long-term hypoglycemic activity of sulphonylurea drugs has been attributed, in part at least, to the stimulation of glucose utilization in extra-pancreatic tissues. The novel sulphonylurea, glimepiride, gives rise to a longer lasting reduction in the
Altan +75 more
core +1 more source
New indications for dabigatran: A suggestion from a drug use evaluation study
Objective: Dabigatran etexilate is a novel oral anticoagulant with several advantages over warfarin such as no need for routine monitoring and fewer drug interactions. This drug was added to our hospital's formulary in 2012.
Farzaneh Ashrafi +2 more
doaj +1 more source
Human Immunodeficiency Virus Infection in Young Adults: Treatment of Substance Use Disorders as a Priority Component of HIV Prevention, Care and Treatment in Low and Middle Income Countries [PDF]
Young adults comprise roughly one-quarter of the global population and are at the developmental stage where personal life goals are formulated and personal independence is obtained.
Kresina TF, Kaplowitz L, Johnson K
core +1 more source
The effect of adherence to statin therapy on cardiovascular mortality : quantification of unmeasured bias using falsification end-points [PDF]
Background: To determine the clinical effectiveness of statins on cardiovascular mortality in practice, observational studies are needed. Control for confounding is essential in any observational study. Falsification end-points may be useful to determine
Bijlsma, Maarten J +3 more
core +9 more sources
Drug utilization review of celecoxib in Ontario [PDF]
Cyclooxygenase (COX)-2-specific inhibitors were developed to circumvent the gastrointestinal toxicity of non-specific non-steroidal anti-inflammatory drugs while maintaining efficacy. However, the higher acquisition cost of COX-2-specific inhibitors has resulted in the implementation of a programme for cost containment in the Ontario public drug ...
J, LeLorier +4 more
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Objective: Teicoplanin is an antibiotic used to treat severe Gram-positive infections, especially those caused by methicillin-resistant Staphylococcus aureus(MRSA).
Masoud Hajialigol +2 more
doaj +1 more source
Kyungim Kim,1,2,* Jinyoung Jung,2,* Haesook Kim,3 Jung Tae Kim,4 Jung Mi Oh,5 Hyunah Kim6,7 1College of Pharmacy, Korea University, Sejong, Republic of Korea; 2Institute of Pharmaceutical Science, Korea University, Sejong, Republic of Korea; 3Department ...
Kim K +5 more
doaj
Drug utilization research: a review
Data from drug utilization research is an invaluable resource for all stake holders involved in drug and health policies. Drug utilization is “marketing, distribution, prescription and use of drugs in a society, with special emphasis on the resulting medical, social and economic consequences”.
Dinesh Kumar Meena, M. Jayanthi
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