Results 41 to 50 of about 16,766,351 (298)

Computational drug repurposing based on electronic health records: a scoping review

npj Digital Medicine, 2022
Computational drug repurposing methods adapt Artificial intelligence (AI) algorithms for the discovery of new applications of approved or investigational drugs.
Nansu Zong, Andrew Wen, Sungrim Moon, Sunyang Fu, Liwei Wang, Yiqing Zhao, Yue Yu, Ming Huang, Yanshan Wang, Gang Zheng, Michelle M. Mielke, James R. Cerhan, Hongfang Liu   +12 more
doaj   +1 more source

Venetoclax‐Based Therapy as a Bridge to Hematopoietic Stem Cell Transplantation in Relapsed or Refractory Pediatric Acute Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Relapsed and/or refractory (R/R) pediatric acute leukemia carries a dismal prognosis, largely driven by chemoresistance to conventional salvage therapy. The BH3‐mimetic venetoclax, combined with chemotherapy or hypomethylating agents, has demonstrated efficacy in small clinical trials.
Katherine S. Colman, Deborah Meyran, Vajiranee Malalasekera, Heather Weerdenburg, Janine Campbell, Rachel Conyers, Stacie Wang, Hannah Walker, Seong Lin Khaw, Diane Hanna   +9 more
wiley   +1 more source

Drug Utilization Review Annual Program Assessment Kansas Medical Assistance Report, Program Assessment for State Fiscal Year ...

, 2009
This Internet resource contains reports issued throughout multiple yearsKansans Health Policy Authority Medical Programs, Program Assessment for State Fiscal Year 2009 Intervention Outcomes, State Fiscal Year 2010 Kansas Health Policy Authority (KHPA ...
Kansas Drug Utilization Review Board
core   +1 more source

Challenges facing drug utilization research in the Latin American region [PDF]

, 2020
Purpose: The International Society of Pharmacoepidemiology (ISPE) in collaboration with the Latin America Drug Utilization Research Group (LatAm DURG), the Medicines Utilization Research in Africa (MURIA) group, and the Uppsala Monitoring Center, is ...
Sales, Maribel, Luis Alesso, Oluka, Margaret N.,, Abraham G. Hartzema, Ogunleye, Olayinka O., Truter, Ilse,, Jorgelina Bernet, Wettermark, Björn,, Horne, Laura,, Massele, Amos, Macarius Donneyong, Lubbe, Martha, Garcia Estrada, Miriam del Carmen,, Arias, Ariel,, Lopes, Luciane C.,, Godman, Brian, Donneyong, Macarius, Joseph Fadare, Amos Massele, Godman, Brian,, Vilaseca, Carmen, Lubbe, Martha,, Bjorn Wettermark, Hartzema, Abraham G.,, Gomez-Galicia, Diana L.,, Comoglio, Raquel Herrera, Appenteng, Kwame,, Ankrah, Daniel, Ankrah, Daniel,, da Cost Lima, Elisangela, Salas, Maribel,, Lopes, Luciane C., Hartzema, Abraham G., Burger, Johanita R., Raquel Herrera Comoglio, Bernet, Jorgelina,, Ilse Truter, Laura Horne, Massele, Amos,, Lima, Elisangela Costa,, Maribel Salas, Diana L. Gómez‐Galicia, Estrada Garcia, Miriam del Carmen, Vilaseca, Carmen,, Olayinka O. Ogunleye, Carmen Vilaseca, Bernet, Jorgelina, Horne, Laura, Fadare, Joseph,, Burger, Johanita R.,, Bergman, Ulf, Donneyong, Macarius,, Appenteng, Kwame, Brian Godman, Bergman, Ulf,, Alesso, Luis, Ariel Arias, Arias, Ariel, Luciane C. Lopes, Margaret N. Oluka, Ogunleye, Olayinka O.,, Wettermark, Bjorn, Kwame Appenteng, Gomez-Galicia, Diana L., Daniel Ankrah, Martha Lubbe, Fadare, Joseph, Ulf Bergman, Alesso, Luis,, Miriam del Carmen Garcia Estrada, Johanita R. Burger, Elisangela da Costa Lima, Comoglio, Raquel Herrera,, Truter, Ilse, Oluka, Margaret N., Burger, Johanita R, Burger, JR, Salas, Maribel, Donneyong, Marcarius, Hartzema, Abraham G, Godman, B,, Truter, I, Wettermark, B,, Donneyong, M, Hartzema, AG, Fadare, J, Lopes, LC, Truter, Isle, Appenteng, K, Salas, M, Lopez, Luciane C   +90 more
core   +1 more source

Biphasic Clinical Course of Pediatric Cytomegalovirus‐Associated Immune Thrombocytopenia: Early Poor Treatment Response but Favorable Long‐Term Outcomes

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Cytomegalovirus (CMV) is a recognized trigger of immune thrombocytopenia (ITP); however, its incidence and impact on disease course in children remain controversial. Therefore, we aimed to characterize the clinical course of pediatric patients with CMV‐associated ITP.
Oded Gilad, Ohad Atia, Osama Tanous, Dafna Brik Simon, Michal Dvori, Miriam Cohen, Tracie A. Goldberg, Efraim Bilavsky, Joanne Yacobovich, Orna Steinberg‐Shemer   +9 more
wiley   +1 more source

Introduction to drug utilization research [PDF]

, 2003
Prepared by the WHO Collaborating Centre for Drug Statistics Methodology, the WHO Collaborating Centre for Drug Utilization Research and Clinical Pharmacological Services, and the International Working Group for Drug Statistics Methodology48 p.Korean ...
WHO International Working Group for Drug Statistics Methodology, WHO Collaborating Centre for Drug Statistics Methodology, WHO Collaborating Centre for Drug Utilization Research and Clinical Pharmacological Services   +2 more
core   +1 more source

Multimodal Implementations to Reduce Neonatal Ventilator-Associated Pneumonia and Colistin Use: An Interrupted Time Series

Antibiotics
Background/Objectives: We investigated multimodal strategies to reduce neonatal ventilator-associated pneumonia (VAP) and antimicrobial use across three periods: period 1 (2014–2017), environmental cleaning with sodium hypochlorite, installation of heat ...
Gunlawadee Maneenil, Anucha Thatrimontrichai, Praew Chareesri, Pattima Pakhathirathien, Manapat Praditaukrit, Supaporn Dissaneevate, Supika Kritsaneepaiboon, Anucha Apisarnthanarak   +7 more
doaj   +1 more source

Bone Mineral Density After Contemporary Treatment for Acute Lymphoblastic Leukaemia: A Matched Cross‐Sectional Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Reduced bone mineral density (BMD) has been reported in survivors of childhood and young adult acute lymphoblastic leukaemia (ALL); however, data from cohorts treated with contemporary protocols and including matched controls remain limited.
Karen Schow Jensen, Mette Tiedemann Skipper, Niels Holtum Birkebæk, Kjeld Schmiegelow, Thomas Leth Frandsen, Bente Langdahl, Rikke Beck Jensen, Asger Roer Pedersen, Christian Mølgaard, Liv Andrés‐Jensen, Birgitte Klug Albertsen   +10 more
wiley   +1 more source

Drug utilization and expenditure of anticancer drugs for breast cancer

Saudi Pharmaceutical Journal, 2020
Purpose: Drug utilization studies have proven to be an effective tool in the evaluation of rational drug use in different health care systems, including oncology. The drug utilization studies were used in many institutes to ensure the safe, effective and
Bander Balkhi, Saeed Alqahtani, Waad Altayyar, Yazeed Ghawaa, Zuhair Alqahtani, Khalid Alsaleh, Yousif Asiri   +6 more
doaj   +1 more source

Social media and internet search data to inform drug utilization: A systematic scoping review

Frontiers in Digital Health, 2023
IntroductionDrug utilization is currently assessed through traditional data sources such as big electronic medical records (EMRs) databases, surveys, and medication sales.
Roman Keller, Roman Keller, Roman Keller, Alessandra Spanu, Milo Alan Puhan, Antoine Flahault, Christian Lovis, Christian Lovis, Margot Mütsch, Raphaelle Beau-Lejdstrom, Raphaelle Beau-Lejdstrom   +10 more
doaj   +1 more source