Results 51 to 60 of about 244,483 (261)
The objective of this study was to determine incidence rate, type, and pattern of clinically relevant potential drug-drug interactions (pDDIs) in a large outpatient population of a developing country.
Ehsan Nabovati +5 more
doaj
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Drug Utilization Review Program Newsletter Drug Utilization Review Bulletin
In 2009 this publication's title changed from Drug Utilization Review Bulletin to Drug Utilization Review Newsletter This internet resource contains several newsletters issued throughout several ...
Kansas. Department of Health and Environment
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In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
This Internet resource contains reports issued throughout multiple yearsKansans Health Policy Authority Medical Programs, Program Assessment for State Fiscal Year 2009 Intervention Outcomes, State Fiscal Year 2010 Kansas Health Policy Authority (KHPA ...
Kansas Drug Utilization Review Board
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Introduction: The utilization of HAMs is crucial in emergency and intensive care departments, as they can cause a significant amount of damage to the patient and health care members if we could not follow the standard treatment guidelines.
Manohar, Dudekula +5 more
core +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Other title: Appropriate Drug Utilization
application/pdf; "Program Outcomes: Evaluating, Measuring, and Identifying Patient Care Benefits and Cost Reduction."; Dates listed represent dates the individual reports were "mailed." All reports were prepared in March 2012 and ...
Health Information Designs.
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Antimicrobial consumption and resistance in a tertiary care hospital in Brazil: a 7-year time series
Introduction: Antimicrobial resistance (AMR) is a major public health challenge globally. This study aimed to analyze the antibacterial consumption (ATBc), and the incidence of multidrug-resistant organisms (MDRO), focusing on pathogens Enterococcus ...
Amanda F Medeiros +9 more
doaj +1 more source

