Results 31 to 40 of about 244,483 (261)

Torsadogenic risk of antipsychotics : combining adverse event reports with drug utilization data across Europe [PDF]

, 2013
Antipsychotics (APs) have been associated with risk of torsade de Pointes (TdP). This has important public health implications. Therefore, (a) we exploited the public FDA Adverse Event Reporting System (FAERS) to characterize their torsadogenic profile; (
Barbui, Corrado, Sturkenboom, Miriam, Barbui Corrado, Marija Kalaba (487415), Miriam Sturkenboom (408749), Barbui, C. (Corrado), Corrado Barbui, Kalaba M, Sturkenboom M, Fabrizio De Ponti (487418), Godman, Brian, Ariola Koci, Raschi, E. (Emanuel), Ponti, F. (Fabrizio) de, Poluzzi Elisabetta, Koci, A. (Ariola), Bjorn Wettermark, Elisabetta Poluzzi, Moretti, U. (Ugo), Miriam Sturkenboom, Godman Brian, Koci Ariola, Bennie, Marion, Brian Godman (487412), Godman B, Moretti U, Moretti Ugo, Koci, Ariola, De Ponti Fabrizio, Godman, B. (Brian), Sturkenboom Miriam, Wettermark B, Sturkenboom, M.C.J.M. (Miriam), Marija Kalaba, Emanuel Raschi (487410), Marion Bennie, Raschi Emanuel, Brian Godman, Kalaba, M. (Marija), Bennie Marion, Wettermark Bjorn, Raschi, Emanuel, Poluzzi, Elisabetta, Ugo Moretti, Elisabetta Poluzzi (487411), De Ponti, Fabrizio, Alfonso Carvajal, Marion Bennie (487416), Ugo Moretti (487414), Ariola Koci (487413), Moretti, Ugo, Wettermark, B. (Bjorn), Kalaba Marija, Poluzzi, E. (Elisabetta), Barbui C, Wettermark, Bjorn, Fabrizio De Ponti, Corrado Barbui (242747), Emanuel Raschi, Kalaba, Marija, Bennie, M. (Marion), Bennie M, Bjorn Wettermark (487417)   +62 more
core   +1 more source

Time Toxicity in Wilms Tumor: Quantifying the Burden of Healthcare Interaction in the First Year After Diagnosis

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Wilms tumor (WT) treatment imposes a significant time burden on patients and their families. Time toxicity is a patient‐centered metric that quantifies the burden of healthcare interaction. We sought to define time toxicity in the first year after diagnosis of WT and hypothesized that it would increase as tumor stage and treatment ...
Caleb Q. Ashbrook, Veerain Gupta, Nicholas J. Clark, Vijay Rings, Lauren E. Corona, Douglass B. Clayton, Daniel J. Benedetti   +6 more
wiley   +1 more source

Current Status and Future Direction of Artificial Intelligence in Healthcare and Medical Education [PDF]

, 2020
The rapid development of artificial intelligence (AI), including deep learning, has led to the development of technologies that may assist in the diagnosis and treatment of diseases, prediction of disease risk and prognosis, health index monitoring, drug
Korean Medical Education Review (의학교육논단)
core   +1 more source

Medication Review: What’s in a Name and What Is It about?

Pharmacy
Background: Medication review is a multifaceted service aimed at optimizing the use of medicines and enhancing the health outcomes of patients. Due to its complexity, it is crucial to clearly describe the service, its variants, and its components to ...
Anneleen Robberechts, Maja Brumer, Victoria Garcia-Cardenas, Niurka M. Dupotey, Stephane Steurbaut, Guido R. Y. De Meyer, Hans De Loof   +6 more
doaj   +1 more source

Social media and internet search data to inform drug utilization: A systematic scoping review

Frontiers in Digital Health, 2023
IntroductionDrug utilization is currently assessed through traditional data sources such as big electronic medical records (EMRs) databases, surveys, and medication sales.
Roman Keller, Roman Keller, Roman Keller, Alessandra Spanu, Milo Alan Puhan, Antoine Flahault, Christian Lovis, Christian Lovis, Margot Mütsch, Raphaelle Beau-Lejdstrom, Raphaelle Beau-Lejdstrom   +10 more
doaj   +1 more source

Emapalumab for Immune Effector Cell‐Associated Hemophagocytic Lymphohistiocytosis‐Like Syndrome Following CD19‐Directed CAR‐T in Two Patients With B‐ALL: Clinical and Biomarker Correlates

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Immune effector cell‐associated hemophagocytic lymphohistiocytosis‐like syndrome (IEC‐HS) is a life‐threatening hyperinflammatory toxicity distinct from cytokine release syndrome (CRS) and neurotoxicity following chimeric antigen receptor T‐cell (CAR‐T) therapy. In a single‐institution retrospective cohort of pediatric and young adult patients
Thomas J. Galletta, Jeremy D. Rubinstein, Christopher E. Dandoy, Ruby Khoury, Angela Faulhaber, Christine L. Phillips, Christa Krupski   +6 more
wiley   +1 more source

Drug utilization and medication costs at the end of life.

, 2022
In the end stages of life, drug treatment goals shift to symptom control and quality of life and as such changes in drug utilization are expected. The aim of this paper is to review the extent to which costs are considered in drug utilization research at
Jansen, K, Haugen, DF, Ruths, S, Schaufel, MA, Pont, L   +4 more
core   +1 more source

The Role of Hematopoietic Cell Transplantation in Ataxia‐Telangiectasia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Ataxia‐telangiectasia (A‐T) is a DNA repair disorder characterized by neurodegeneration, immunodeficiency, and cancer predisposition. Hematopoietic cell transplantation (HCT) is an established therapy in related disorders such as Fanconi anemia (FA) and Nijmegen breakage syndrome (NBS), but its role in A‐T is unclear.
Laila Alkhouli, Seth Rotz, Masatoshi Takagi, Richa Sharma   +3 more
wiley   +1 more source

Potential drug interactions : exposure and management in hospital and ambulatory settings [PDF]

, 2006
Health care professionals are responsible to ensure safe dispensing and use of drug regimens involving the use of drug combinations that may interact and cause serious adverse events.
Indermitte, Jörg Lorenz
core   +1 more source

Efficacy and Safety Analysis of Roxarestat in Regulating Renal Anemia in Patients on Maintenance Hemodialysis

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Objective To compare the efficacy and safety of roxarestat versus recombinant human erythropoietin (rhEPO) in the management of renal anemia in patients undergoing maintenance hemodialysis. Methods This was a prospective, open‐label, randomized controlled trial.
Lingling Chen, Junjie Zhu, Qiaonan Ge
wiley   +1 more source