Results 101 to 110 of about 4,947,726 (309)

Selected references on essential drugs

, 1992
ONLINEWHO/DAP/92.14.
World Health Organization. Action Programme on Essential Drugs and Vaccines
core  

Reports of side effects associated with the use of drugs 1985 [PDF]

, 1985
Halothane In the ten year period of 1970 to 1980 the Board received 9 reports of hepatitis (2 fatal) associated with the repeated use of halothane. This mirrors experience in other countries.
National Drugs Advisory Board (NDAB)
core  

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Availability of Emergency Drugs and Essential Equipment in Intensive Care Units in Hospitals of Ethiopia: A Multicenter Cross-Sectional Study

Open Access Emergency Medicine, 2020
Metages Hunie,1 Tiruwork Desse,2 Efrem Fenta,1 Diriba Teshome,1 Moges Gelaw,1 Amanu Gashaw3 1Department of Anesthesia, School of Medicine, College of Health Sciences, Debre Tabor University, Debre Tabor, Ethiopia; 2Department of Internal Medicine, School
Hunie M, Desse T, Fenta E, Teshome D, Gelaw M, Gashaw A   +5 more
doaj  

Reports of side effects associated with the use of drugs 1984

, 1984
During 1984 the National Drugs Advisory Board received 803 reports, from which 1668 side-effects were recorded. Of these, the largest percentages were as follows: Drugs Affecting the Central Nervous System 50% (including Non-Steroidal Anti-lnfammatory
National Drugs Advisory Board (NDAB)
core  

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Malaria case management: Enabling appropriate use of ACTs

International Journal of Infectious Diseases, 2014
E.N. Wesangula, D. Memusi, J. Mbului, R. Kolute   +3 more
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Guidelines for evaluating an essential drugs programme

, 1985
ONLINEDAP/85.8.
World Health Organization. Action Programme on Essential Drugs and Vaccines
core  

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source