Results 111 to 120 of about 4,947,726 (309)
Analysis of essential drugs lists of a regional healthcare coordination center in Rio Grande do Sul
In Brazil municipalities are responsible for initiating the guarantee of access to essential medicines by selecting those that will be included in their lists. This study aimed to analyze how the Municipal Lists of Essential Medicines (MLEM) are prepared,
Mariele Salvi +3 more
doaj
Reports of side effects associated with the use of drugs 1976
The National Drugs Advisory Board received 463 reports in all during 1976. From these 844 adverse reactions were recorded associated with the use of drugs during the year. There were 13 cases of drug interactions - these are listed separately.
National Drugs Advisory Board (NDAB)
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The challenge of synthetic drugs in East and South-East Asia and Oceania [PDF]
The demand for synthetic drugs in East and Southeast Asia and Oceania continues to rise, while rapid economic integration is creating new opportunities for transnational criminal groups to expand the illicit drug trade, warns the United Nations Office on
Justice Tettey
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Translophagy—A potential link between autophagy impairment and translational errors
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Potential conflicts in the fight against counterfeit drugs [PDF]
This analysis looks at the best way to deal with the proliferation of fake drugs, and considers the conflict that arises when government agencies aim to reduce the harmful effects of the fake medicine trade while the pharmaceutical firms seek profit ...
Luis Currais, Berta Rivera, Paolo Rungo
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Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
In addition to an earlier survey "Smoking, alcohol consumption and the use of drugs by schoolchildren from the age of ten" (Steinmetz Archive Nr. P1057) among pupils of regular schools, pupils of schools for special education have been interviewed about ...
Zwart, W.M. de, Berben, E.G.M.J., Nederlands instituut voor alcohol en drugs, NIAD * Utrecht (primary investigator)
core +1 more source
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil +3 more
wiley +1 more source
Action Programme on Essential Drugs : 96-97 report of the biennium
WHO/DAP/MAC(10)/98.4108 ...
WHO Action Programme on Essential Drugs
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