Results 11 to 20 of about 6,707,659 (315)

Natural Products as Sources of New Drugs over the Nearly Four Decades from 01/1981 to 09/2019.

open access: yesJournal of Natural Products, 2020
This review is an updated and expanded version of the five prior reviews that were published in this journal in 1997, 2003, 2007, 2012, and 2016. For all approved therapeutic agents, the time frame has been extended to cover the almost 39 years from the ...
D. Newman, G. Cragg
semanticscholar   +1 more source

Analysis of therapeutic targets for SARS-CoV-2 and discovery of potential drugs by computational methods

open access: yesActa Pharmaceutica Sinica B, 2020
SARS-CoV-2 has caused tens of thousands of infections and more than one thousand deaths. There are currently no registered therapies for treating coronavirus infections. Because of time consuming process of new drug development, drug repositioning may be
Canrong Wu   +12 more
semanticscholar   +1 more source

KEGG: new perspectives on genomes, pathways, diseases and drugs

open access: yesNucleic Acids Res., 2016
KEGG (http://www.kegg.jp/ or http://www.genome.jp/kegg/) is an encyclopedia of genes and genomes. Assigning functional meanings to genes and genomes both at the molecular and higher levels is the primary objective of the KEGG database project.
M. Kanehisa   +4 more
semanticscholar   +1 more source

Platinum-based drugs for cancer therapy and anti-tumor strategies

open access: yesTheranostics, 2022
Platinum-based drugs cisplatin, carboplatin, and oxaliplatin are widely used for chemotherapeutic eradication of cancer. However, the side effects of platinum drugs, such as lack of selectivity, high systemic toxicity, and drug resistance, seriously ...
Chunyu Zhang   +3 more
semanticscholar   +1 more source

Physical and Chemical Properties and Quality Control Methods of Hyaluronic Acid (Review)

open access: yesРазработка и регистрация лекарственных средств, 2020
Introduction. This review describes the physicochemical properties that determine the use of hyaluronic acid in ophthalmology. We have studied methods for determining hyaluronic acid using various analytical methods.Text.
A. Kh. Amandusova   +6 more
doaj   +1 more source

Acknowledgement to Reviewers of Marine Drugs in 2013

open access: yesMarine Drugs, 2014
The editors of Marine Drugs would like to express their sincere gratitude to the following reviewers for assessing manuscripts in ...
Marine Drugs Editorial Office
doaj   +1 more source

Drug-Drug Interaction of Antifungal Drugs

open access: yesYAKUGAKU ZASSHI, 2005
This article reviews the in vitro metabolic and the in vivo pharmacokinetic drug-drug interactions with antifungal drugs, including fluconazole, itraconazole, micafungin, miconazole, and voriconazole. In the in vitro interaction studies, the effects of antifungal drugs on specific activities of cytochrome P450s (CYPs), including CYP1A2, CYP2C9, CYP2C19,
Toshiro, Niwa   +2 more
openaire   +3 more sources

Pharmacodynamic Drug–Drug Interactions [PDF]

open access: yesClinical Pharmacology & Therapeutics, 2019
Pharmacodynamic drug–drug interactions (DDIs) occur when the pharmacological effect of one drug is altered by that of another drug in a combination regimen. DDIs often are classified as synergistic, additive, or antagonistic in nature, albeit these terms are frequently misused.
Jin, Niu   +2 more
openaire   +2 more sources

PEGylated nanographene oxide for delivery of water-insoluble cancer drugs. [PDF]

open access: yesJournal of the American Chemical Society, 2008
It is known that many potent, often aromatic drugs are water insoluble, which has hampered their use for disease treatment. In this work, we functionalized nanographene oxide (NGO), a novel graphitic material, with branched polyethylene glycol (PEG) to ...
Zhuang Liu   +3 more
semanticscholar   +1 more source

Acknowledgement to Reviewers of Marine Drugs in 2014

open access: yesMarine Drugs, 2015
The editors of Marine Drugs would like to express their sincere gratitude to the following reviewers for assessing manuscripts in 2014:[...]
Marine Drugs Editorial Office
doaj   +1 more source

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