Results 21 to 30 of about 6,242,441 (357)

Drug-Drug Interaction of Antifungal Drugs

YAKUGAKU ZASSHI, 2005
This article reviews the in vitro metabolic and the in vivo pharmacokinetic drug-drug interactions with antifungal drugs, including fluconazole, itraconazole, micafungin, miconazole, and voriconazole. In the in vitro interaction studies, the effects of antifungal drugs on specific activities of cytochrome P450s (CYPs), including CYP1A2, CYP2C9, CYP2C19,
Toshiro, Niwa, Toshifumi, Shiraga, Akira, Takagi   +2 more
openaire   +3 more sources

Pharmacodynamic Drug–Drug Interactions [PDF]

Clinical Pharmacology & Therapeutics, 2019
Pharmacodynamic drug–drug interactions (DDIs) occur when the pharmacological effect of one drug is altered by that of another drug in a combination regimen. DDIs often are classified as synergistic, additive, or antagonistic in nature, albeit these terms are frequently misused.
Jin, Niu, Robert M, Straubinger, Donald E, Mager   +2 more
openaire   +2 more sources

Acknowledgement to Reviewers of Marine Drugs in 2015

Marine Drugs, 2016
The editors of Marine Drugs would like to express their sincere gratitude to the following reviewers for assessing manuscripts in 2015. [...]
Marine Drugs Editorial Office
doaj   +1 more source

Improvement of macrolactins production by the genetic adaptation of Bacillus siamensis A72 to saline stress via adaptive laboratory evolution

Microbial Cell Factories, 2022
Background Macrolactins, a type of macrolide antibiotic, are toxic to the producer strains. As such, its level is usually maintained below the lethal concentration during the fermentation process.
Yuman Gan, Meng Bai, Xiao Lin, Kai Liu, Bingyao Huang, Xiaodong Jiang, Yonghong Liu, Chenghai Gao   +7 more
doaj   +1 more source

Analysis of prescription and dispensation of psychotropic medications in two cities in the State of São Paulo, Brazil [PDF]

Brazilian Journal of Psychiatry, 2002
OBJECTIVES: To investigate the prescription and dispensation of psychotropic medications through the analysis of the prescriptions/notices kept at various institutions in two cities in the state of São Paulo. METHODS: The prescriptions kept at drugstores,
Ana Regina Noto, Elisaldo de A Carlini, Patrícia C Mastroianni, Vanete C Alves, José Carlos F Galduróz, Wagner Kuroiwa, Jussara Csizmar, Agrimeron Costa, Mariluci de A Faria, Sônia Regina Hidalgo, Dirce de Assis, Solange Aparecida Nappo   +11 more
doaj   +1 more source

Chondroitin Sulfate/Dermatan Sulfate Hybrid Chains from Swim Bladder: Isolation, Structural Analysis, and Anticoagulant Activity

Marine Drugs, 2023
Glycosaminoglycans (GAGs) with unique structures from marine animals show intriguing pharmacological activities and negligible biological risks, providing more options for us to explore safer agents.
Yue Yao, Hao Tang, Haiqiong Ma, Zidong Liu, Jinwen Huang, Xiufen Yang, Longyan Zhao, Qingxia Yuan   +7 more
doaj   +1 more source

Antiepileptic drugs reduce serum uric acid [PDF]

, 1987
Uric acid examination in 554 epileptic out-patients under long-term anticonvulsant medication revealed significantly lower serum concentrations compared to a group of normal controls.
Arab, Bernhard Schellenberg, Heinrich Schmidt-Gayk, Klaus-Henning Krause, Meinardi, Peter Berlit, Richens, Yeung   +7 more
core   +1 more source

The Integrated Model of Quality Management System of Laboratory Studies of Medicines (Review)

Разработка и регистрация лекарственных средств, 2021
Introduction. The publication is devoted to the role of laboratory research in ensuring the quality of domestic medicines and is a review and analysis of regulatory documents and current publications on this topic.Text.
A. I. Selezneva, V. A. Smirnov, V. V. Goryachkin, N. N. Chadova, S. V. Polyakov, V. N. Shestakov, R. A. Abramovich   +6 more
doaj   +1 more source

Repurposing drugs to target nonalcoholic steatohepatitis [PDF]

, 2019
Nonalcoholic fatty liver disease (NAFLD) is a complex disorder that has evolved in recent years as the leading global cause of chronic liver damage.
Pirola, Carlos José, Sookoian, Silvia Cristina   +1 more
core   +1 more source

Drug–Drug Noninteractions

Cardiovascular Therapeutics, 2009
Understanding and documentation of drug–drug interactions (DDIs) are an important component of drug development, and of clinical therapeutics. Because clinical DDI studies are costly, time‐consuming, and involve some risk, not all clinical DDI questions can be realistically addressed through human DDI trials.In vitromodels have been used to identify ...
openaire   +2 more sources