Results 71 to 80 of about 8,070,517 (356)
Inhibition of the PI3K but not the MEK/ERK pathway sensitizes human glioma cells to alkylating drugs
Cancer Cell International, 2018 Background Intrinsic chemoresistance of glioblastoma (GBM) is frequently owed to activation of the PI3K and MEK/ERK pathways. These signaling cascades are tightly interconnected however the quantitative contribution of both to intrinsic resistance is ...
Bodo Haas +12 more
doaj +1 more source
Mitochondrial DNA. Part B. Resources, 2021 Echinoderms (Echinodermata) are morphologically diverse and ecologically important groups of marine invertebrate, many of which are key components of local benthic ecosystem.
Shengping Zhong +4 more
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Reduced bone mineral density (BMD) has been reported in survivors of childhood and young adult acute lymphoblastic leukaemia (ALL); however, data from cohorts treated with contemporary protocols and including matched controls remain limited.
Karen Schow Jensen +10 more
wiley +1 more source
Recent Advances in Chemistry and Bioactivities of Secondary Metabolites from the Genus Acremonium
Journal of FungiAcremonium fungi is one of the greatest and most complex genera in Hyphomycetes, comprising 130 species of marine and terrestrial sources. The past decades have witnessed substantial chemical and biological investigations on the diverse secondary ...
Yuning Qin +6 more
doaj +1 more source
Reports of side effects associated with the use of drugs 1982 [PDF]
, 1982 The National Drugs Advisory Board received 540 reports during 1982 from which 1051 side-effects were reported. 39% of the reactions received occurred in association with drugs affecting the central nervous system, over half concerned analgesics, 18% of
National Drugs Advisory Board (NDAB)
core
Pediatric Blood &Cancer, EarlyView.ABSTRACT Pediatric intramedullary low‐grade gliomas (PIMLGGs) are rare neoplasms that present unique clinical and management challenges. Although surgery remains the primary tool for tissue diagnosis and decompression, complete gross‐total resection is frequently unfeasible due to the infiltrative nature of these lesions.
Olga M. Sergeenko +5 more
wiley +1 more source
Journal of Analytical Methods in ChemistryRosuvastatin calcium is a widely used 3-hydroxy-3-methylglutaryl coenzyme A-reductase inhibitor developed for the treatment of dyslipidemia. To establish a control strategy for the elemental impurities, a new digestion method combined with an inductively
Yajie Hao +7 more
doaj +1 more source
Trials, 2020 Background Unemployment is highly prevalent in populations with alcohol and drug dependence and the employment support offered in addiction-treatment programmes is ineffective.
John Marsden +9 more
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Adult survivors of childhood acute lymphoblastic leukemia (ALL) are at risk of reduced exercise capacity, decreased physical activity levels, persistent fatigue, and neurocognitive deficits. The aim was to investigate exercise capacity and physical activity levels of adult survivors of childhood ALL and their associations with ...
Laura Jess +5 more
wiley +1 more source
Recreational Use of Nitrous Oxide – a Growing Concern in Europe
Emerging Trends in Drugs, Addictions, and HealthIntroduction: Nitrous oxide, commonly known as laughing gas, is used medically as an analgesic and anaesthetic. It has been used recreationally for its brief euphoric effects for over 200 years, however, in the last decade, there has been a large ...
J. De Morais +16 more
doaj +1 more source