Results 81 to 90 of about 3,598,260 (304)

National Drugs Advisory Board annual report and accounts, 1994

open access: yes, 1994
The National Drugs Advisory Board was established by the Minister for Health in 1966 by the National Drugs Advisory Board (Establishment) Order 1966 (5.1. No. 163 of 1966) under the Health (Corporate Bodies) Act 1961.
National Drugs Advisory Board (NDAB)
core  

Effect of RNA Demethylase FTO Overexpression on Biomass and Bioactive Substances in Diatom Phaeodactylum tricornutum

open access: yesBiology
Phaeodactylum tricornutum is rich in bioactive substances, rendering it valuable in nutrition and medicine. Epigenetic editing mediated by human RNA demethylase FTO can significantly increase the yields of rice and potato and offers significant potential
Yanan Yang   +4 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Reports of side effects associated with the use of drugs 1976

open access: yes, 1977
The National Drugs Advisory Board received 463 reports in all during 1976. From these 844 adverse reactions were recorded associated with the use of drugs during the year. There were 13 cases of drug interactions - these are listed separately.
National Drugs Advisory Board (NDAB)
core  

Local and regional drugs task forces: handbook.

open access: yes, 2011
This handbook has been developed within the context of the institutional structures recommended under the National Drugs Strategy 2009-2016 and within the overall framework of the National Social Inclusion Plan 2007-2016.
Drugs Advisory Group
core   +1 more source

Recent Advances in Anti-Inflammatory Compounds from Marine Microorganisms

open access: yesMarine Drugs
Marine microbial secondary metabolites with diversified structures have been found as promising sources of anti-inflammatory lead compounds. This review summarizes the sources, chemical structures, and pharmacological properties of anti-inflammatory ...
Guihua Yang   +9 more
doaj   +1 more source

Lost in the Vaso‐Occlusion: A Patient's Abdominal Pain Returns With a Vengeance

open access: yes
Pediatric Blood &Cancer, EarlyView.
Dunia Hatabah   +5 more
wiley   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Characteristics of product recalls of biopharmaceuticals and small-molecule drugs in the USA [PDF]

open access: yes, 2016
Compared with chemically synthesized small-molecule drugs, the manufacturing process of biopharmaceuticals is more complex. Unexpected changes to product characteristics following manufacturing changes have given rise to calls for robust systems to ...
Mantel-Teeuwisse, Aukje K   +7 more
core   +2 more sources

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

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