Results 91 to 100 of about 3,598,260 (304)
National Drugs Advisory Board annual report 1975
, 1975 By the end of 1975. the National Drugs Advisory Board had 15 months of experience in the management of mandatory licensing systems for medicinal products and for manufacturers of pharmaceuticals in Ireland. With few exceptions.
National Drugs Advisory Board (NDAB)
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FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
FEBS Letters, EarlyView.Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
Reports of side effects associated with the use of drugs 1986
, 1986 During 1986 the National Drugs Advisory Board received 1,188 reports of adverse reactions from which 2,454 side effects were recorded. These results represent an increase of approximately 20% in reporting.
National Drugs Advisory Board (NDAB)
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Stem Cell Research & Therapy, 2017 Background Pluripotent stem cells (PSCs) such as embryonic stem cells and induced pluripotent stem cells are promising target cells for cell regenerative medicine together with recently advanced technology of in-vitro differentiation.
Seok-Jin Kang +7 more
doaj +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Report of side effects associated with the use of drugs 1981
, 1981 The National Drugs Advisory Board received 662 reports during 1981 from which 1264 side-effects were recorded. Of these 33.3% concerned drugs affecting the central nervous system and 27% involved anti-infective drugs. Of the drugs affecting the central
National Drugs Advisory Board (NDAB)
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What can we learn from clinical trials of anticonvulsant drugs in epilepsy?
, 2002 Any physician who intends to utilize the available antiepileptic drugs (AEDs) judiciously, cannot do so without being well versed on their pharmacological properties and the large body of evidence that is continuously accumulating on their relative ...
What Can We Learn From Clinical Trials Of Anticonvulsant Drugs In Epilepsy? +1 more
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FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Reports of side effects associated with the use of drugs 1984
, 1984 During 1984 the National Drugs Advisory Board received 803 reports, from which 1668 side-effects were recorded. Of these, the largest percentages were as follows: Drugs Affecting the Central Nervous System 50% (including Non-Steroidal Anti-lnfammatory
National Drugs Advisory Board (NDAB)
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