Results 121 to 130 of about 31,224 (320)

Correlation of retinal fluid and photoreceptor and RPE loss in neovascular AMD by automated quantification, a real‐world FRB! analysis

Acta Ophthalmologica, Volume 103, Issue 3, Page 295-303, May 2025.
Abstract Purpose To quantify ellipsoid zone (EZ) loss during anti‐VEGF therapy for neovascular age‐related macular degeneration (nAMD) and correlate these findings with nAMD disease activity using artificial intelligence‐based algorithms. Methods Spectral domain optical coherence tomography (Spectralis, Heidelberg Engineering) images from nAMD ...
Virginia Mares, Gregor S. Reiter, Markus Gumpinger, Oliver Leigang, Hrvoje Bogunovic, Daniel Barthelmes, Marcio B. Nehemy, Ursula Schmidt‐Erfurth   +7 more
wiley   +1 more source

INFLUENCE OF OPTIC NERVE DRUSEN ON VISUAL FUNCTIONS IN CHILDREN AND ADOLESCENTS WITH ESSENTIAL ARTERIAL HYPERTENSION

Acta Biomedica Scientifica, 2016
The article presents data examination of children and male adolescents, aged 8 to 17 years without eye pathologies, with primary hypertension diagnosis - established at the clinic of Scientific Centre for Family Health and Human Reproduction Problems ...
A. G. Shchuko, T. N. Lureva, Y. N. Savina, D. Y. Samsonov   +3 more
doaj   +1 more source

Peptide redesign for inhibition of the complement system: Targeting age-related macular degeneration. [PDF]

, 2016
PurposeTo redesign a complement-inhibiting peptide with the potential to become a therapeutic for dry and wet age-related macular degeneration (AMD).MethodsWe present a new potent peptide (Peptide 2) of the compstatin family.
Cabrera, Andrea P, Ghosh, Kaustabh, Gorham, Ronald D, Harrison, Reed ES, Johnson, Lincoln V, Mohan, Rohith R, Morikis, Dimitrios   +6 more
core   +1 more source

Drusen Volume as a Predictor of Disease Progression in Patients With Late Age-Related Macular Degeneration in the Fellow Eye.

Investigative Ophthalmology and Visual Science, 2016
PURPOSE Increasing drusen volume was proposed to be a predictor of disease progression in age-related macular degeneration (AMD). In patients with late AMD in one eye, the fellow eyes without neovascularization are known to be at higher risk of ...
N. Abdelfattah, Hongyang Zhang, D. Boyer, P. Rosenfeld, W. Feuer, Giovanni Gregori, S. Sadda   +6 more
semanticscholar   +1 more source

The value of age of onset and family history as predictors of molecular diagnosis in a Swedish cohort of inherited retinal disease

Acta Ophthalmologica, Volume 103, Issue 3, Page 327-338, May 2025.
Abstract Purpose This study aimed to characterize clinical and genetic findings in a Swedish cohort with inherited retinal disease (IRD), identify predictors for achieving a molecular diagnosis and evaluate the effects of increased genetic testing over time.
Karl De Geer, Stefan Löfgren, Anna Lindstrand, Malin Kvarnung, Erik Björck   +4 more
wiley   +1 more source

Retinal Angiomatous Proliferation in an Eye with Cuticular Drusen

Case Reports in Ophthalmology, 2015
Purpose: To report the presence of retinal angiomatous proliferation (RAP) in an eye with cuticular drusen detected by fluorescein and indocyanine green angiography by confocal scanning laser ophthalmoscopy and by spectral-domain optical coherence ...
Atsuko Sato, Nami Senda, Emi Fukui, Kouichi Ohta   +3 more
doaj   +1 more source

Evaluation of Transfer Learning for Classification of: (1) Diabetic Retinopathy by Digital Fundus Photography and (2) Diabetic Macular Edema, Choroidal Neovascularization and Drusen by Optical Coherence Tomography [PDF]

arXiv, 2019
Deep learning has been successfully applied to a variety of image classification tasks. There has been keen interest to apply deep learning in the medical domain, particularly specialties that heavily utilize imaging, such as ophthalmology. One issue that may hinder application of deep learning to the medical domain is the vast amount of data necessary
arxiv  

Natural products targeting tumour angiogenesis

British Journal of Pharmacology, Volume 182, Issue 10, Page 2094-2136, May 2025.
Abstract Tumour angiogenesis is the formation of new blood vessels to support the growth of a tumour. This process is critical for tumour progression and metastasis, making it an attractive approach to cancer therapy. Natural products derived from plants, animals or microorganisms exert anti‐angiogenic properties and can be used to inhibit tumour ...
Xiaohua Lu, Lara Johanna Friedrich, Thomas Efferth   +2 more
wiley   +1 more source

System analysis of factors in the pathogenesis of drusen formation in AMD

Journal of Ophthalmology, 2020
Background: Age-related macular degeneration (AMD) is a major cause of visual loss in elderly individuals. However, the involvement of cell receptors in the initiation of retinal disorder in AMD has not been duly reflected in the literature.
S.Yu. Mogilevskyy, Kh.V. Kovalchuk
doaj   +1 more source

Assessment of Generative Adversarial Networks Model for Synthetic Optical Coherence Tomography Images of Retinal Disorders [PDF]

, 2019
Purpose: To assess whether a generative adversarial network (GAN) could synthesize realistic optical coherence tomography (OCT) images that satisfactorily serve as the educational images for retinal specialists and the training datasets for the classification of various retinal disorders using deep learning (DL).
arxiv   +1 more source