Results 41 to 50 of about 68,553 (259)

The Mesoscopic Damage Mechanism of Jointed Sandstone Subjected to the Action of Dry–Wet Alternating Cycles

Applied Sciences
The effect of the dry–wet cycle, characterized by periodic water level changes in the Three Gorges Reservoir, will severely degrade the bearing performance of rock formations.
Liang Zhang, Guilin Wang, Runqiu Wang, Bolong Liu, Ke Wang   +4 more
doaj   +1 more source

Study on Mix Proportion Design Based on Strength and Sulfate Resistance of 100% Recycled Aggregate Concrete

Buildings, 2022
This paper presents the mechanical properties of 100% recycled aggregate concrete (RAC), and the results and analysis of the dry–wet cycle accelerated sulfate attack test. The results show that recycled concrete aggregate (RCA) can replace the coarse and
Haizhou Li, Jianping Liu, Fujiao Chu, Lu Zhang   +3 more
doaj   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

FEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson, Tomáš Gedeon, Mauricio Garcia Benitez, Campbell Putnam, William R. Harcombe, Radhakrishnan Mahadevan, Ashley E. Beck   +6 more
wiley   +1 more source

Prediction for Humidity Adjustment Factor and Dry-Wet Cycle Reduction Factor of Resilient Modulus of Subgrade Soil Based on ANN

Zhongwai Gonglu
Existing methods for determining the humidity adjustment factor and dry-wet cycle reduction factor of the resilient modulus of subgrade soil are mostly based on laboratory tests that consume a large amount of manpower and time, and the prediction ...
WANG Xufeng, FU Wei, PENG Junhui, HU Jiankun, ZHANG Junhui, LI Zhiguang   +5 more
doaj   +1 more source

Effects of Acidic Environment on Dynamic Mechanical Properties and Porosity Evolution Characteristics of Coal

Shock and Vibration, 2021
Coal pillars left in coal mines are often subjected to long-term submersion by groundwater and chemical solutions and are susceptible to deterioration and even destabilization damage under dynamic load disturbance.
Shuang Gong, Xiaojun Li, Wen Wang, Shibin Yao, Juan Liu, Dengyun Niu   +5 more
doaj   +1 more source

Wet/dry cycle durability of polyphenylene ionomer membranes in PEFC

Journal of Power Sources Advances, 2021
The mechanical durability of our hydrocarbon polymer electrolyte membrane, poly(sulfophenylene quinquephenylene) (SPP-QP) or polyphenylene ionomer, was evaluated in wet/dry cycle tests in fuel cells according to the US-DOE protocol, where the effect of ...
Toshiki Tanaka, Haruhiko Shintani, Yasushi Sugawara, Akihiro Masuda, Nobuyuki Sato, Makoto Uchida, Kenji Miyatake   +6 more
doaj   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Strength characteristics and microstructure of silty sand improved by red mud, lime and fly ash under dry-wet cycle

Case Studies in Construction Materials
Red mud is a kind of solid waste, which can be used as engineering roadbed filler after proper treatment. Due to the special physical and chemical properties of red mud, such as high liquid limit and high plasticity index, it may affect the stability of ...
Song Yin, Siyue Zheng, Xinming Li, Zhiliu Wang, Pan Yan, Ya He, Yuru Li   +6 more
doaj   +1 more source

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

FEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart, Manon Van den Abbeel, Christoph Schifflers, Karim Bouhjar, Andrea Scarmelotto, Alexis Khelfi, Anne‐Catherine Wera, Carine Michiels   +7 more
wiley   +1 more source