Results 41 to 50 of about 1,294,477 (268)

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

A Review of Age-related Macular Degeneration and Current Concepts in Management

TNOA Journal of Ophthalmic Science and Research
Age-related macular degeneration (AMD) is a prevalent and progressive retinal disease that affects a substantial number of elderly individuals worldwide.
Sahebaan Sethi
doaj   +1 more source

FRICTION COEFICIENT OF SEMI-SPHERICAL RUBBER PROTRUSIONS SLIDING AGAINST RUBBER [PDF]

Journal of the Egyptian Society of Tribology, 2013
It is necessary to reduce slip and fall in bathrooms, workshops, kid gardens, halls and walking yards. The present work aims to test the frictional behavior of rubber semi-spherical balls of different diameter and hardness to have specific information ...
Y. M. El-Sherbiny, Y. G. Al-Qaham, W. Y. Ali   +2 more
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

FRICTION COEFFICIENT OF RUBBER SLIDING AGAINST DUSTY INDOOR FLOORING [PDF]

Journal of the Egyptian Society of Tribology, 2010
It is well known that in Middle East airborne contaminant levels are particularly high. During severe storm conditions dust concentrations of the order of 100 to 500 times higher may be encountered.
A. M. Samy, W. Y. Ali, Y. M. El-Sherbiny
doaj   +1 more source

Effects of Three Drying Methods on Drying Quality of Mu-jujube at Different Harvest Periods

Shipin gongye ke-ji, 2023
In order to make full use of jujube resources and further explore the processing and utilization value of jujube fruit, the changes of jujube nutrition, color and quality indexes after natural drying, hot air drying and vacuum freeze-drying in different ...
Jianchun SHI, Yu WANG, Zhigang LI, Xiaoling HAO, Lingzhi GAO, Changli SONG   +5 more
doaj   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

Vitamin D and vitamin B12 profiles in children with primary nocturnal enuresis, an analytical cross-sectional study

Annals of Medicine
Purpose To outline the prevalence of vitamin D and vitamin B12 deficiencies in enuretic children.Methods An analytical descriptive study was conducted on enuretic children who were followed up at the outpatient clinic for nocturnal enuresis at the ...
Hoda Atef Abdelsattar Ibrahim, Shymaa Sobhy Menshawy, Fatma E. Hassan, Shirin M. El-Makawi, Omnia Raafat Amn, Nermeen Bastawy, Samar Saad, Shadia M.Hussein, Dina Mahmoud, Khaled Mohamed Abdelhamid ElKhashab   +9 more
doaj   +1 more source