Results 71 to 80 of about 1,646,698 (308)

Prevalence of Dry Eye syndrome in a South African diabetic paediatric population: a single-centre based case study.

, 2023
Masters Degree. University of KwaZulu-Natal, Durban.Background: Diabetes Mellitus is a chronic condition resulting from elevated blood glucose levels.
Bisetty, Seyuri.
core  

Inhibition of VEGF‐Induced Angiogenesis and Vascular Leakage by Bicistronic Co‐Expression of Aflibercept and COMP‐Ang1

Advanced Healthcare Materials, EarlyView.
A bicistronic rAAV8 vector encoding Aflibercept (Afb) and COMP‐cAng1 simultaneously coordinates VEGF clearance and Tie2‐mediated vessel maturation. In a 3D angiogenesis‐on‐a‐chip model, rAAV8‐Afb/cAng1 effectively reverses pathological barrier breakdown under clinical disease‐mimicking challenges.
Bong‐Kyu Kim, Jaehong Min, Sang‐Hee Park, Subeen Shin, Sangbin Yu, Jeong‐Eun Park, Sujin Kim, Wooju Park, Jihoon Ko, Sunjong Kwon   +9 more
wiley   +1 more source

Water‐Soluble, Enzyme‐Degradable, and Hydrolyzable STAR Particles for Enhanced Drug Delivery to Skin

Advanced Healthcare Materials, EarlyView.
Biodegradable polymer STAR particles fabricated from water‐soluble, enzyme‐degradable, and hydrolyzable materials significantly enhance intradermal drug delivery. By replacing conventional non‐biodegradable materials, these STAR particles address environmental and safety concerns while expanding the potential of skin‐based drug delivery technologies ...
Aydin Sadeqi, Gülçin Arslan Azizoğlu, Mark R. Prausnitz   +2 more
wiley   +1 more source

Parainflammation in the Ocular System: Considerations on the Underlying Mechanisms and Treatment of Dry Eye Disease

Ophthalmology and Therapy
Introduction The transition from regulated to dysregulated parainflammation is a new concept that needs to be elucidated to clarify the pathogenesis of dry eye disease (DED).
Stefano Barabino, Pasquale Aragona, Christophe Baudouin, Kostas Boboridis, José Salgado-Borges, Jose M. Benitez-del-Castillo, Elisabeth M. Messmer, Adriana Stanila, Jutta Horwath-Winter, Edward Wylegala, Maurizio Rolando   +10 more
doaj   +1 more source

From Cell‐Derived Vesicles to Hybrid Nanovectors: Biological Membranes as Functional Blueprints for Gene Delivery

Advanced Healthcare Materials, EarlyView.
Biologically derived and hybrid nonviral nanovectors are examined as distinct but convergent design approaches. Integrating synthetic components with biologically functionalized membranes allows efficient interactions with complex cellular environments.
Clara Baldari, Claudia Leone, Gabriella Leccese, Claudia De Stradis, Alessandra Invidia, Concetta Quintarelli, Biagio De Angelis, Franco Locatelli, Giuseppe Gigli, Gabriele Maiorano, Ilaria Elena Palamà   +10 more
wiley   +1 more source

Automatic Dry Eye Detection [PDF]

, 2007
Dry Eye Syndrome is a common disease in the western world, with effects from uncomfortable itchiness to permanent damage to the ocular surface. Nevertheless, there is still no objective test that provides reliable results. We have developed a new method for the automated detection of dry areas in videos taken after instilling fluorescein in the tear ...
Tamir Yedidya, Richard I. Hartley, Jean-Pierre Guillon, Yogesan Kanagasingam   +3 more
openaire   +3 more sources

Photovoltaic Stimulation of Mouse and Pig Retina With Pyrolytic Carbon Microelectrodes Integrated on High‐Density Silicon Solar Cell Arrays

Advanced Healthcare Materials, EarlyView.
In this study, we fabricate photovoltaic retinal implants with pyrolytic carbon electrodes and test their ability to stimulate mouse and pig retinas when illuminated with near‐infrared light. We find increased spiking activity in both animal models compared to spontaneous activity and TTX controls and analyze the spike amplitude, latency and frequency.
Akihiro Matsumoto, Pratik Kusumanchi, Jesper Guldsmed Madsen, Asbjørn Cortnum Jørgensen, Gisele Alves dos Reis Benatto, Sune Thorsteinsson, Peter Behrensdorff Poulsen, Keisuke Yonehara, Toke Bek, Stephan Sylvest Keller, Rasmus Schmidt Davidsen   +10 more
wiley   +1 more source

Symptomatic dry eye disease and associated factors among postgraduate students at Hawassa University, Sidama Region, Ethiopia

Scientific Reports
Dry eye disease and its symptoms are becoming an increasingly significant public health issue. This study aims to understand the extent of the disease, particularly in light of the post-COVID digital revolution.
Mikias Mered Tilahun, Henok Biruk Alemayehu, Biruk Lelisa Eticha, Getasew Alemu Mersha, Melkamu Temeselew Tegegn, Tarekegn Cheklie Zeleke, Nardos Hussen Abdulkadir, Abdisa Gemedi Jara, Ermias Solomon Yalew, Kalkidan Berhane Tsegaye, Merkineh Markos Lorato   +10 more
doaj   +1 more source

New drugs for the treatment of dry eye disease

, 2015
William H Ridder III, Apoorva Karsolia Southern California College of Optometry, Marshall B Ketchum University, Fullerton, CA, USA Abstract: Dry eye disease (DED) is one of the most commonly encountered conditions for eye care practitioners.
Ridder III WH, Karsolia A
core  

Diagnosing dry eye with dynamic-area high-speed videokeratoscopy [PDF]

, 2011
Dry eye syndrome is one of the most commonly reported eye health conditions. Dynamic-area highspeed videokeratoscopy (DA-HSV) represents a promising alternative to the most invasive clinical methods for the assessment of the tear film surface quality ...
Turuwhenua, Jason, David Alonso-Caneiro, Alonso-Caneiro, David, Michael J. Collins, D. Robert Iskander, Iskander, D. Robert, Jason Turuwhenua, Collins, Michael J.   +7 more
core   +2 more sources