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Tear and ocular surface disease biomarkers: A diagnostic and clinical perspective for ocular allergies and dry eye disease.

Experimental Eye Research, 2022
Validated biomarkers to be used as biological tools for managing ocular surface diseases (OSDs) are still an unmet need in daily clinical practice. Many studies have contributed to the already extensive list of candidate biomarkers for these disorders ...
T. Suárez-Cortés   +2 more
semanticscholar   +1 more source

Rosacea and Dry Eye Disease

Ocular Immunology and Inflammation, 2022
Ocular rosacea is a chronic potentially sight-threatening inflammatory condition, which can occur in approximately 20% of patients without skin involvement. However, an accurate diagnosis of ocular rosacea has not been defined yet due to its rather nonspecific symptoms and clinical findings.
Bianka Sobolewska   +2 more
openaire   +2 more sources

Pigment epithelium-derived factor (PEDF) plays anti-inflammatory roles in the pathogenesis of dry eye disease.

The ocular surface, 2021
PURPOSE To investigate the expression of pigment epithelium-derived factor (PEDF) in ocular surface in dry eye disease (DED) and its anti-inflammatory roles and mechanisms, clinically and by experiments in vivo and in vitro.
B. Ma   +10 more
semanticscholar   +1 more source

Allergy and Dry Eye Disease

Ocular Immunology and Inflammation, 2021
Ocular allergy (OA) and dry eye disease (DED) are the most common ocular surface disorders with a potential severe impact on the patient's quality of life. OA and DED may coexist and have a significant clinical overlap. Therefore, clinical features commonly believed to be distinctive of OA or DED may be sometimes insufficient for a differential ...
Leonardi A., Modugno R. L., Salami E.
openaire   +3 more sources

Dry eye disease and proteomics

The Ocular Surface, 2022
Dry eye disease (DED) is a highly prevalent disease worldwide mostly associated with age, though other factors such as screen use and contact lens wear explain why it is increasingly diagnosed in younger people. DED also disproportionately affects women.
Catherine Joan Jackson   +3 more
openaire   +2 more sources

Pathophysiology of dry eye disease and novel therapeutic targets.

Experimental Eye Research, 2022
The pathophysiology of Dry Eye Disease (DED) is complex, and therapy may be a challenge. Tear film instability, tear film hyperosmolarity, ocular surface damage and ocular surface inflammation are accepted key events in the pathogenesis of the disease ...
E. Messmer
semanticscholar   +1 more source

Dry Eye Disease

2020
DED is one of the most commonly encountered ocular surface diseases affecting millions of people. The severity varies over a wide spectrum and there are multiple diagnostic and treatment options available. Most of the cases are managed by conservative treatment. Newer treatment modalities helps improve patient compliance.
Rashmi Deshmukh, Essam A. El Toukhy
openaire   +1 more source

Neurostimulation for dry eye disease

Current Opinion in Allergy & Clinical Immunology, 2022
Purpose of review To review the neuroanatomy and physiology of the basal and reflex tearing and present the available and developing therapies using the concept of neurostimulation in dry eye disease (DED). Recent findings The most prevalent current DED treatments seek to supplement
Nir, Erdinest   +3 more
openaire   +2 more sources

Dry Eyes Disease. A review

Czech and Slovak Ophthalmology, 2020
This article provides a comprehensive view of the issue of dry eye. It emphasizes provisions of the Tear Film and Ocular Surface Society, discusses the new classification and definition of dry eye based on its pathophysiology, and emphasizes the correct diagnostic and therapeutic approaches, which appears in the form of algorithms.Dry eye is a ...
openaire   +2 more sources

Treatment of Dry Eye Disease

The Consultant Pharmacist, 2016
Review of the etiology, clinical manifestations, and treatment of dry eye disease (DED).Articles indexed in PubMed (National Library of Medicine), Iowa Drug Information Service (IDIS), and the Cochrane Reviews and Trials in the last 10 years using the key words "dry eye disease," "dry eye syndrome," "dry eye and treatment." Primary sources were used to
Leisa L, Marshall, J Michael, Roach
openaire   +2 more sources

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