Results 31 to 40 of about 383,592 (314)
Analysis of the pathogenic factors and management of dry eye in ocular surface disorders [PDF]
, 2017 The tear film represents the interface between the eye and the environment. The alteration of the delicate balance that regulates the secretion and distribution of the tear film determines the dry eye (DE) syndrome. Despite having a multifactorial origin,
Albietz +14 more
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Desiccating stress-induced disruption of ocular surface immune tolerance drives dry eye disease [PDF]
, 2016 Dry eye is an allegedly autoimmune disorder for which the initiatingmechanisms and the targeted antigens in the ocular surface are not known,yet there is extensive evidence that a localized T helper type 1 (Th1)/Th17effector T cell response is ...
Galletti, Jeremías Gastón +5 more
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NORTHWEST JOURNAL OF MEDICAL SCIENCES, 2022 INTRODUCTION: The term Dry eye can be attributed to the Swedish ophthalmologist Henrik S.C. Sjogren. He was the first to refer to the triad of dry eye, dry mouth, and joint pain in his original thesis in 1933 Zur kenntnis der keratoconjuctivitis sicca.
openaire +1 more source
The Interblink Interval in Normal and Dry Eye Subjects [PDF]
, 2013 Purpose: Our aim was to extend the concept of blink patterns from average interblink interval (IBI) to other aspects of the distribution of IBI. We hypothesized that this more comprehensive approach would better discriminate between normal and dry eye ...
Abelson, Mark Barry +4 more
core +1 more source
Prevalence of dry eye disease among healthy Egyptian population
Journal of the Egyptian Ophthalmological Society, 2020 Purpose The aim was to study the prevalence and related risk factors of dry eye disease (DED) in a random population sample from Cairo and upper Egypt. Materials and methods A clinic-based, cross-sectional, observational, multicenter study was conducted ...
Bassem F Aziz, Caroline A Tawfik
doaj +1 more source
Safety and efficacy clinical trials for SYL1001, a novel short interfering RNA for the treatment of dry eye disease [PDF]
, 2016 PURPOSE. To evaluate the efficacy and safety of SYL1001, a short interfering (si) RNA targeting the transient receptor potential cation channel subfamily V member 1 (TRPV1), for the treatment of dry eye disease (DED). METHODS. This study combines a phase
Benitez-Del-Castillo, José Manuel +13 more
core +2 more sources
Sex Disparity in How Pain Sensitivity Influences Dry Eye Symptoms. [PDF]
, 2019 PurposeWomen have a higher dry eye disease prevalence compared with men, although only relatively minor differences in the ocular surface have been observed.
Li, Wing, Lin, Meng C
core
Aging and dry eye disease [PDF]
Experimental Gerontology, 2012 Dry eye disease is a prevalent eye disorder that in particular affects the elderly population. One of the major causes of dry eye, meibomian gland dysfunction (MGD), shows increased prevalence with aging. MGD is caused by hyperkeratinization of the ductal epithelium of meibomian gland and reduced quantity and/or quality of meibum, the holocrine product
Juan, Ding, David A, Sullivan
openaire +2 more sources
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
The Relationship Between Dry Eye Disease and Digital Screen Use
Clinical Ophthalmology, 2021 Zaina Al-Mohtaseb,1 Scott Schachter,2 Bridgitte Shen Lee,3 Jaclyn Garlich,4 William Trattler5 1Department of Ophthalmology, Cullen Eye Institute, Baylor College of Medicine, Houston, TX, USA; 2Presbyopia and Ocular Surface Disease, Allergan, an AbbVie ...
Al-Mohtaseb Z +4 more
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